Detailed information NTG0910249

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: SD437_RS17685
• Genome accession: NZ_CP139565
• Coordinates: 3499798..3500961 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain NCCP
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3494798..3505961

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SD437_RS17655	-	3495063..3495482 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
SD437_RS17660	comFC	3495556..3496245 (-)	690	WP_201741798.1	phosphoribosyltransferase family protein	Machinery gene
SD437_RS17665	-	3496251..3496535 (-)	285	WP_003151389.1	competence protein ComFB	-
SD437_RS17670	comFA	3496593..3497978 (-)	1386	WP_104842867.1	DEAD/DEAH box helicase	Machinery gene
SD437_RS17675	-	3498086..3498934 (-)	849	WP_003151387.1	DegV family protein	-
SD437_RS17680	degU	3499032..3499721 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
SD437_RS17685	degS	3499798..3500961 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
SD437_RS17690	-	3501184..3501831 (+)	648	WP_007614107.1	YigZ family protein	-
SD437_RS17695	-	3501836..3503029 (+)	1194	WP_151140083.1	LCP family protein	-
SD437_RS17700	-	3503129..3504205 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
SD437_RS17705	-	3504337..3505533 (-)	1197	WP_017418813.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=910249 SD437_RS17685 WP_007407484.1 3499798..3500961(-) (degS) [Bacillus velezensis strain NCCP]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=910249 SD437_RS17685 WP_007407484.1 3499798..3500961(-) (degS) [Bacillus velezensis strain NCCP]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATTATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951