Detailed information NTG0909533

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SM123_RS05450
• Genome accession: NZ_CP139419
• Coordinates: 1159653..1160885 (+)
• Length: 410 a.a.
• NCBI ID: WP_049493014.1
• Uniprot ID: A0A1F1CCL8
• Organism: Streptococcus lingualis strain S5
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1154653..1165885

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SM123_RS05445 (SM123_05445)	-	1158935..1159444 (+)	510	WP_320909164.1	dihydrofolate reductase	-
SM123_RS05450 (SM123_05450)	clpX	1159653..1160885 (+)	1233	WP_049493014.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SM123_RS05455 (SM123_05455)	yihA	1160897..1161499 (+)	603	WP_003016353.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
SM123_RS05460 (SM123_05460)	-	1161649..1162353 (+)	705	WP_021153281.1	glucosaminidase domain-containing protein	-
SM123_RS05465 (SM123_05465)	-	1162520..1163317 (+)	798	WP_070594841.1	formate/nitrite transporter family protein	-
SM123_RS05470 (SM123_05470)	rplJ	1163552..1164052 (+)	501	WP_003001722.1	50S ribosomal protein L10	-
SM123_RS05475 (SM123_05475)	rplL	1164128..1164496 (+)	369	WP_003001622.1	50S ribosomal protein L7/L12	-
SM123_RS05480 (SM123_05480)	-	1164735..1165178 (+)	444	WP_023918201.1	hypothetical protein	-
SM123_RS05485 (SM123_05485)	-	1165326..1165778 (+)	453	WP_003007432.1	hypothetical protein	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45677.18 Da
• Isoelectric Point: 4.3940

>NTDB_id=909533 SM123_RS05450 WP_049493014.1 1159653..1160885(+) (clpX) [Streptococcus lingualis strain S5]
MPTNQNNDMMVYCSFCGKSQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREDETDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGKNNKAIDESSSYMQEIVAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDNVELEFDDEALQEIANKAIERKTGARGLRSIIEETMMDVMFEIPSQEDVKLVRITKEAVD
GTEKPILETA

Nucleotide

• Length: 1233 bp

>NTDB_id=909533 SM123_RS05450 WP_049493014.1 1159653..1160885(+) (clpX) [Streptococcus lingualis strain S5]
ATGCCAACGAATCAAAATAATGATATGATGGTTTATTGTTCATTTTGCGGAAAGAGTCAAGATGAAGTCCAAAAAATCAT
TGCAGGAAACAACGCGTTTATCTGTAATGAATGTGTCGAGTTAGCACAAGAAATTATCCGTGAGGAGCTAGCAGAAGAAG
TTCTTGCAGACCTTAGCGAAGTTCCAAAACCAATCGAATTGCTCAATATCTTGAACCACTATGTGATCGGTCAAGATCGT
GCCAAACGTGCTCTTGCTGTAGCGGTATATAACCACTACAAACGCATCAACTTCCACGATACGCGCGAAGACGAGACAGA
TGTTGAATTGCAAAAATCAAACATCCTCATGATTGGTCCTACTGGTTCAGGTAAGACTTTCTTGGCCCAAACCTTGGCTC
GTAGCCTGAATGTTCCATTTGCTATTGCAGATGCAACAGCTTTAACTGAAGCCGGTTATGTGGGTGAAGACGTTGAAAAT
ATTCTCTTAAAACTTCTTCAGGCAGCGGATTTCAATATTGAGCGTGCAGAACGTGGCATCATCTATGTCGATGAAATTGA
TAAGATCGCTAAGAAAAGTGAAAACGTCTCGATTACACGTGACGTTTCTGGTGAAGGGGTGCAACAAGCTCTCTTGAAGA
TCATCGAAGGAACTGTCGCTAGTGTACCACCTCAAGGGGGACGTAAACACCCTCAACAAGAGATGATCCAAGTGGACACC
AAGAACATCCTCTTTATCGTAGGTGGGGCTTTTGATGGGATCGAAGAAATTGTTAAGCAACGTCTTGGTGAAAAAATCAT
CGGTTTCGGTAAGAACAATAAAGCTATTGATGAATCCAGCTCTTACATGCAAGAAATCGTTGCGGAAGATATTCAAAAAT
TTGGGATTATCCCAGAATTGATCGGACGTCTTCCAGTCTTTGCTGCTCTTGAGCAATTGACAGTTGACGATCTTGTCCGT
ATCTTGAAAGAGCCACGCAATGCTCTGGTAAAACAATACCAAACCTTACTCTCTTATGATAATGTTGAATTGGAATTTGA
TGACGAAGCTCTTCAAGAGATTGCGAATAAAGCCATCGAAAGAAAAACAGGAGCTCGTGGACTTCGTTCGATTATCGAAG
AAACCATGATGGATGTCATGTTTGAAATTCCAAGTCAAGAAGATGTCAAACTTGTTCGAATCACAAAAGAAGCTGTTGAC
GGAACAGAAAAACCAATTCTTGAAACAGCCTAG

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (313-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-306)

3D structure

• AlphaFold DB: A0A1F1CCL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	86.585	100	0.866
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.463	98.049	0.563