Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SM121_RS09295 Genome accession   NZ_CP139418
Coordinates   1888156..1889454 (-) Length   432 a.a.
NCBI ID   WP_320910893.1    Uniprot ID   -
Organism   Streptococcus dentalis strain S1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1883156..1894454
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM121_RS09285 (SM121_09285) hpf 1886870..1887412 (-) 543 WP_320910891.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SM121_RS09290 (SM121_09290) - 1887494..1888159 (-) 666 WP_320910892.1 ComF family protein -
  SM121_RS09295 (SM121_09295) comFA/cflA 1888156..1889454 (-) 1299 WP_320910893.1 DEAD/DEAH box helicase Machinery gene
  SM121_RS09300 (SM121_09300) - 1889510..1890151 (+) 642 WP_320910894.1 YigZ family protein -
  SM121_RS09305 (SM121_09305) cysK 1890274..1891197 (+) 924 WP_003012578.1 cysteine synthase A -
  SM121_RS09310 (SM121_09310) - 1891248..1891613 (-) 366 WP_023920312.1 S1 RNA-binding domain-containing protein -
  SM121_RS09315 (SM121_09315) - 1891615..1893015 (-) 1401 WP_021154563.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SM121_RS09320 (SM121_09320) - 1893060..1893692 (-) 633 WP_155127850.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49529.56 Da        Isoelectric Point: 9.3590

>NTDB_id=909509 SM121_RS09295 WP_320910893.1 1888156..1889454(-) (comFA/cflA) [Streptococcus dentalis strain S1]
MKIEDSYGRLLTESQMTNDLKEIAQEFPAIEKQNGRYQCFRCGSLIDQKLWKLSEEVLYCRACIQLGRIRSDQKLYAIGQ
QDFEGKEVLNWKGTLTSYQQEVSEGLIQAVKAGKHALVHAVTGAGKTEMMYQVVATAIKAGKAVCIATPRIDVCIELYGR
MEEDFSCSISLLHGESEPYFRTPLVIATTHQLLKFYQAFDLLIIDEVDAFPYVDNPILYKAAQNAIKKEGNTLYLTATST
DELDKKVKKKEIIRYSLPRRFHGNPLVVPKIKWVPKIREKIEKGRIPYELLQLIKKQRQTHYPLLIFVSEIELGQQFTEN
LKKYFPKETVGFVSSQTTDRLRMVEEFRNRAITMLVSTTILERGVTFPFVDVFVLESNHKLFTKSTLVQISGRVGRSKER
PTGKLLFLSDGITREMKKAIKEIKEMNQEAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=909509 SM121_RS09295 WP_320910893.1 1888156..1889454(-) (comFA/cflA) [Streptococcus dentalis strain S1]
ATGAAGATAGAAGATTCTTATGGAAGACTCTTAACGGAGAGTCAAATGACAAATGATCTAAAAGAAATTGCCCAAGAATT
TCCAGCTATAGAAAAACAGAATGGAAGGTACCAATGCTTTCGATGTGGCAGTTTGATTGATCAAAAACTGTGGAAGTTGA
GTGAAGAGGTACTGTATTGTAGAGCCTGTATCCAATTGGGAAGGATCCGGAGTGATCAAAAACTTTATGCTATTGGACAG
CAAGACTTTGAAGGAAAAGAGGTGCTAAACTGGAAAGGGACCTTGACTTCCTATCAACAAGAGGTATCTGAAGGACTTAT
CCAAGCAGTTAAAGCAGGAAAACATGCCTTGGTACATGCTGTGACAGGAGCTGGAAAAACGGAAATGATGTACCAGGTTG
TAGCAACAGCGATCAAGGCAGGAAAAGCAGTCTGTATTGCTACCCCAAGAATCGATGTCTGTATAGAATTGTACGGAAGG
ATGGAGGAAGATTTTTCCTGCTCCATCTCTTTGCTTCATGGAGAATCAGAGCCCTATTTTAGAACGCCTTTAGTGATCGC
TACAACCCACCAATTGCTAAAGTTTTATCAGGCCTTTGATCTCCTTATTATAGATGAGGTAGATGCTTTTCCATATGTGG
ATAATCCAATCTTATATAAAGCAGCTCAGAATGCAATAAAAAAAGAGGGGAATACCCTATATTTGACAGCAACCTCTACA
GATGAGTTAGATAAAAAGGTCAAGAAAAAAGAAATCATTCGTTATAGTCTCCCAAGAAGATTTCATGGGAACCCACTAGT
GGTCCCTAAAATAAAATGGGTGCCGAAAATTAGAGAAAAAATAGAAAAAGGAAGAATCCCTTACGAACTATTGCAACTGA
TCAAGAAACAAAGACAGACTCACTACCCATTGTTAATCTTTGTATCTGAAATAGAATTAGGACAACAATTCACTGAGAAC
TTAAAAAAATACTTTCCCAAAGAAACAGTAGGTTTTGTATCCTCACAGACAACAGACCGTCTACGAATGGTAGAAGAGTT
TAGAAACAGAGCCATAACCATGCTAGTCTCTACAACTATTTTAGAAAGAGGAGTGACCTTTCCGTTTGTAGATGTCTTTG
TTTTAGAAAGTAATCATAAATTATTTACTAAAAGTACCCTCGTACAAATTTCAGGAAGGGTCGGTCGAAGTAAAGAAAGA
CCAACAGGTAAACTACTTTTCCTATCAGATGGCATAACACGAGAAATGAAGAAAGCGATCAAAGAAATAAAGGAAATGAA
TCAGGAGGCTGGATTTTGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(290-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

60.277

100

0.604
  comFA/cflA Streptococcus pneumoniae D39

60.277

100

0.604
  comFA/cflA Streptococcus pneumoniae R6

60.277

100

0.604
  comFA/cflA Streptococcus mitis SK321

60.046

100

0.602
  comFA/cflA Streptococcus pneumoniae TIGR4

60.046

100

0.602
  comFA/cflA Streptococcus mitis NCTC 12261

59.815

100

0.6
  comFA Lactococcus lactis subsp. cremoris KW2

50.251

92.13

0.463
  comFA Latilactobacillus sakei subsp. sakei 23K

37.644

100

0.377