Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABRA90_RS15860 Genome accession   NZ_CP158308
Coordinates   3285200..3285856 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CM2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3280200..3290856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABRA90_RS15825 (ABRA90_15815) dcyD 3281080..3282066 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ABRA90_RS15830 (ABRA90_15820) tcyL 3282081..3282749 (+) 669 WP_350337424.1 cystine ABC transporter permease -
  ABRA90_RS15835 (ABRA90_15825) tcyN 3282746..3283498 (+) 753 WP_001273007.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABRA90_RS15840 (ABRA90_15830) sdiA 3283728..3284450 (+) 723 WP_001154279.1 transcriptional regulator SdiA -
  ABRA90_RS15845 (ABRA90_15835) yecF 3284517..3284741 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABRA90_RS15850 (ABRA90_15840) yecU 3284728..3284904 (-) 177 WP_000590347.1 protein YecU -
  ABRA90_RS15855 (ABRA90_15845) - 3284987..3285058 (-) 72 Protein_3091 transcriptional regulator -
  ABRA90_RS15860 (ABRA90_15850) letA 3285200..3285856 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABRA90_RS15865 (ABRA90_15855) uvrC 3285853..3287685 (+) 1833 WP_001283415.1 excinuclease ABC subunit UvrC Machinery gene
  ABRA90_RS15870 (ABRA90_15860) pgsA 3287742..3288290 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABRA90_RS15890 (ABRA90_15880) yecA 3288940..3289605 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=908224 ABRA90_RS15860 WP_000611335.1 3285200..3285856(+) (letA) [Escherichia coli strain CM2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=908224 ABRA90_RS15860 WP_000611335.1 3285200..3285856(+) (letA) [Escherichia coli strain CM2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486