Detailed information NTG0908063

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SON02_RS06240
• Genome accession: NZ_CP139211
• Coordinates: 1419948..1421147 (-)
• Length: 399 a.a.
• NCBI ID: WP_135027832.1
• Uniprot ID: -
• Organism: Streptococcus sp. LysM4
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1414948..1426147

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SON02_RS06220 (SON02_06205)	-	1414993..1415901 (-)	909	WP_135027844.1	diacylglycerol/lipid kinase family protein	-
SON02_RS06225 (SON02_06210)	dnaN	1416283..1417419 (-)	1137	WP_135027841.1	DNA polymerase III subunit beta	-
SON02_RS06230 (SON02_06215)	dnaA	1417568..1418926 (-)	1359	WP_135027837.1	chromosomal replication initiator protein DnaA	-
SON02_RS06235 (SON02_06220)	spo0J	1419128..1419892 (-)	765	WP_135027834.1	ParB/RepB/Spo0J family partition protein	Regulator
SON02_RS06240 (SON02_06225)	htrA	1419948..1421147 (-)	1200	WP_135027832.1	S1C family serine protease	Regulator
SON02_RS06245 (SON02_06230)	rlmH	1421322..1421801 (+)	480	WP_135027828.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SON02_RS06250 (SON02_06235)	-	1421826..1422497 (+)	672	WP_135027825.1	YoaK family protein	-

Sequence

Protein

• Length: 399 a.a.
• Molecular weight: 42235.54 Da
• Isoelectric Point: 4.7602

>NTDB_id=908063 SON02_RS06240 WP_135027832.1 1419948..1421147(-) (htrA) [Streptococcus sp. LysM4]
MKKFLKVLLLLFIGFIGGLAGTLATPLLQTNKQVTQIVETKKENEETTVSKVQYNNENSTTSAVEKVQNAVVSVINYQQP
RDNGYRSILEESGNSDDLAVAGEGSGVIYKKTDQFAYLVTNTHVIAGAEKIDIQLASGEKVEGELIGSDTYADIAVIKIT
ADKVKNVAEFADSDKIKVGETAIAIGSPLGSIYANTVTQGIVSSLSRTVTSKAEDGQTISTNAIQTDTAINPGNSGGPLI
NIQGQVIGITSSKITSSSNSAAGVAVEGMGFAIPANDAVNIINQLEKNGKVIRPALGIKMANLSNLSTTQRQKAGIEDDS
LKSGIVVLSTQKGLPADGQLEQYDVITKIDGETVETISDLQSALYKHTVGDTMSITYSRRGKEKTVDIKLTNSTEDLTN

Nucleotide

• Length: 1200 bp

>NTDB_id=908063 SON02_RS06240 WP_135027832.1 1419948..1421147(-) (htrA) [Streptococcus sp. LysM4]
ATGAAAAAATTCTTAAAAGTATTACTCTTATTATTCATTGGGTTTATAGGAGGATTAGCAGGAACACTTGCCACACCTTT
GCTCCAGACGAATAAGCAAGTCACTCAAATTGTTGAAACCAAAAAAGAAAATGAAGAGACAACTGTTAGTAAGGTACAGT
ACAATAATGAAAATTCAACAACATCAGCTGTTGAGAAAGTACAAAATGCAGTAGTATCCGTCATTAATTATCAACAACCG
CGTGATAATGGCTATCGTTCTATTTTAGAAGAGAGTGGCAATTCAGATGATCTGGCTGTAGCAGGAGAAGGTTCTGGAGT
TATTTATAAAAAAACAGACCAATTTGCCTATCTCGTCACCAATACCCACGTGATTGCAGGAGCTGAAAAAATTGATATTC
AACTAGCTTCGGGTGAAAAAGTGGAAGGGGAGTTGATTGGTTCAGATACTTATGCAGATATTGCCGTGATTAAAATTACA
GCTGATAAGGTTAAAAATGTTGCTGAATTTGCAGATTCTGACAAGATTAAGGTCGGAGAAACAGCGATTGCCATTGGTAG
CCCACTCGGTAGTATCTACGCAAACACAGTAACACAAGGAATCGTTTCTAGTCTCAGCCGTACAGTCACTTCAAAAGCAG
AAGATGGTCAAACTATTTCCACCAATGCCATTCAAACCGATACAGCGATTAACCCTGGAAATTCAGGCGGCCCACTAATC
AATATTCAAGGACAAGTCATCGGAATTACCTCTAGTAAAATCACTTCTAGCTCCAATTCAGCAGCTGGAGTTGCTGTAGA
AGGAATGGGATTTGCTATTCCAGCAAATGATGCAGTGAATATCATCAATCAACTAGAGAAAAATGGAAAAGTCATCCGTC
CAGCACTGGGGATTAAAATGGCGAATTTAAGCAATCTTTCTACCACACAACGACAAAAAGCAGGTATTGAAGATGATAGC
TTGAAATCAGGTATTGTGGTTCTTTCTACTCAAAAAGGCTTACCAGCAGACGGTCAATTAGAACAATATGATGTTATCAC
CAAAATTGATGGCGAAACAGTCGAAACAATTAGTGATTTACAAAGCGCCCTCTATAAACATACTGTTGGTGATACGATGT
CCATTACCTACTCTCGCCGTGGAAAAGAAAAAACAGTTGACATCAAATTAACCAATTCAACAGAGGATCTCACAAACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (294-390)

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

• Peptidase family M50 (Peptidase_M50) (236-394)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	61.25	100	0.614
htrA	Streptococcus mutans UA159	60.349	100	0.607
htrA	Streptococcus pneumoniae Rx1	57.935	99.499	0.576
htrA	Streptococcus pneumoniae D39	57.935	99.499	0.576
htrA	Streptococcus pneumoniae R6	57.935	99.499	0.576
htrA	Streptococcus pneumoniae TIGR4	57.935	99.499	0.576
htrA	Streptococcus mitis NCTC 12261	57.935	99.499	0.576