Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   SGW57_RS13315 Genome accession   NZ_CP139025
Coordinates   2646336..2647022 (-) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain DA70484     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2641336..2652022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGW57_RS13295 rpsT 2642250..2642501 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  SGW57_RS13300 holA 2642546..2643520 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  SGW57_RS13305 comEC 2643577..2645778 (-) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SGW57_RS13310 - 2645783..2646244 (-) 462 WP_000439692.1 ComE operon protein 2 -
  SGW57_RS13315 comEA 2646336..2647022 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  SGW57_RS13320 - 2647062..2647778 (-) 717 WP_000084835.1 class I SAM-dependent methyltransferase -
  SGW57_RS13325 rsfS 2647781..2648134 (-) 354 WP_001088020.1 ribosome silencing factor -
  SGW57_RS13330 yqeK 2648135..2648719 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  SGW57_RS13335 nadD 2648709..2649278 (-) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  SGW57_RS13340 yhbY 2649281..2649571 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  SGW57_RS13345 aroE 2649575..2650381 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  SGW57_RS13350 yqeH 2650395..2651495 (-) 1101 WP_001280134.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=906800 SGW57_RS13315 WP_001794049.1 2646336..2647022(-) (comEA) [Staphylococcus aureus strain DA70484]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=906800 SGW57_RS13315 WP_001794049.1 2646336..2647022(-) (comEA) [Staphylococcus aureus strain DA70484]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952