Detailed information NTG0906767

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGW57_RS01105
• Genome accession: NZ_CP139025
• Coordinates: 156111..157154 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain DA70484
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 151111..162154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGW57_RS01075	-	151532..152788 (-)	1257	WP_001793983.1	aminopeptidase	-
SGW57_RS01080	-	152791..152991 (-)	201	WP_000180460.1	DUF1128 family protein	-
SGW57_RS01085	-	153138..153602 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
SGW57_RS01090	-	153609..153884 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SGW57_RS01095	-	154162..155379 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
SGW57_RS01100	vraR	155492..156121 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGW57_RS01105	vraS	156111..157154 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGW57_RS01110	liaF	157151..157852 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGW57_RS01115	-	157867..158253 (-)	387	WP_001110178.1	hypothetical protein	-
SGW57_RS01120	map	158470..159228 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SGW57_RS01125	-	159868..160854 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
SGW57_RS01130	-	161043..161456 (-)	414	WP_001643743.1	hypothetical protein	-
SGW57_RS01135	-	161485..161595 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=906767 SGW57_RS01105 WP_001017131.1 156111..157154(-) (vraS) [Staphylococcus aureus strain DA70484]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=906767 SGW57_RS01105 WP_001017131.1 156111..157154(-) (vraS) [Staphylococcus aureus strain DA70484]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1