Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABL174_RS10325 Genome accession   NZ_CP157672
Coordinates   2146479..2147135 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ST-131     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2141479..2152135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABL174_RS10295 (ABL174_10295) dcyD 2142358..2143344 (+) 987 WP_001128232.1 D-cysteine desulfhydrase -
  ABL174_RS10300 (ABL174_10300) tcyL 2143359..2144027 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ABL174_RS10305 (ABL174_10305) tcyN 2144024..2144776 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABL174_RS10310 (ABL174_10310) sdiA 2145006..2145728 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  ABL174_RS10315 (ABL174_10315) yecF 2145796..2146020 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABL174_RS10320 (ABL174_10320) yecU 2146007..2146183 (-) 177 WP_001307856.1 protein YecU -
  ABL174_RS10325 (ABL174_10325) letA 2146479..2147135 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABL174_RS10330 (ABL174_10330) uvrC 2147132..2148964 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ABL174_RS10335 (ABL174_10335) pgsA 2149021..2149569 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABL174_RS10355 (ABL174_10355) - 2150153..2151169 (-) 1017 WP_001531780.1 tyrosine-type recombinase/integrase -
  ABL174_RS10360 (ABL174_10360) - 2151138..2151401 (-) 264 WP_000833838.1 DUF4224 domain-containing protein -
  ABL174_RS10365 (ABL174_10365) - 2151611..2151793 (-) 183 WP_000916334.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=906243 ABL174_RS10325 WP_000611328.1 2146479..2147135(+) (letA) [Escherichia coli strain ST-131]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=906243 ABL174_RS10325 WP_000611328.1 2146479..2147135(+) (letA) [Escherichia coli strain ST-131]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482