Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABLU29_RS11230 Genome accession   NZ_CP157498
Coordinates   2164372..2165001 (-) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis strain 2B-5     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2159372..2170001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABLU29_RS11205 (ABLU29_11195) - 2160302..2161546 (-) 1245 WP_311916259.1 FtsW/RodA/SpoVE family cell cycle protein -
  ABLU29_RS11210 (ABLU29_11200) - 2161767..2162372 (-) 606 WP_003131406.1 TVP38/TMEM64 family protein -
  ABLU29_RS11215 (ABLU29_11205) - 2162369..2162800 (-) 432 WP_003131405.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  ABLU29_RS11220 (ABLU29_11210) - 2162802..2163392 (-) 591 WP_012897543.1 peptidylprolyl isomerase -
  ABLU29_RS11225 (ABLU29_11215) - 2163495..2164301 (-) 807 WP_058212722.1 Cof-type HAD-IIB family hydrolase -
  ABLU29_RS11230 (ABLU29_11220) vraR 2164372..2165001 (-) 630 WP_003131402.1 response regulator transcription factor Regulator
  ABLU29_RS11235 (ABLU29_11225) - 2165029..2166027 (-) 999 WP_012897540.1 sensor histidine kinase -
  ABLU29_RS11240 (ABLU29_11230) liaF 2166024..2166653 (-) 630 WP_012897539.1 cell wall-active antibiotics response protein LiaF -
  ABLU29_RS11245 (ABLU29_11235) rpsN 2166819..2167088 (-) 270 WP_010905608.1 30S ribosomal protein S14 -
  ABLU29_RS11250 (ABLU29_11240) - 2167186..2168484 (-) 1299 WP_058212720.1 LCP family protein -
  ABLU29_RS11255 (ABLU29_11245) - 2168515..2169714 (-) 1200 WP_058212719.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=906005 ABLU29_RS11230 WP_003131402.1 2164372..2165001(-) (vraR) [Lactococcus lactis strain 2B-5]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=906005 ABLU29_RS11230 WP_003131402.1 2164372..2165001(-) (vraR) [Lactococcus lactis strain 2B-5]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGATTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACTCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACGAGTTTTATTGATGACGAAAAAGTTTTTCCGGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATTGCATCTGCAATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGATGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416