Detailed information NTG0904475

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGW63_RS12235
• Genome accession: NZ_CP138670
• Coordinates: 2449778..2450821 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017133.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain DA70500
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2444778..2455821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGW63_RS12205	-	2445145..2445255 (+)	111	WP_001790257.1	hypothetical protein	-
SGW63_RS12210	-	2445284..2445697 (+)	414	WP_001549145.1	hypothetical protein	-
SGW63_RS12215	-	2446187..2447173 (-)	987	WP_031811349.1	aromatic acid exporter family protein	-
SGW63_RS12220	map	2447704..2448462 (+)	759	WP_000636144.1	type I methionyl aminopeptidase	-
SGW63_RS12225	-	2448679..2449065 (+)	387	WP_001110179.1	hypothetical protein	-
SGW63_RS12230	liaF	2449080..2449781 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGW63_RS12235	vraS	2449778..2450821 (+)	1044	WP_001017133.1	sensor histidine kinase	Regulator
SGW63_RS12240	vraR	2450811..2451440 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGW63_RS12245	-	2451552..2452769 (-)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
SGW63_RS12250	-	2453047..2453322 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
SGW63_RS12255	-	2453329..2453793 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SGW63_RS12260	-	2453940..2454140 (+)	201	WP_000180463.1	DUF1128 family protein	-
SGW63_RS12265	-	2454143..2455399 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40043.54 Da
• Isoelectric Point: 6.2447

>NTDB_id=904475 SGW63_RS12235 WP_001017133.1 2449778..2450821(+) (vraS) [Staphylococcus aureus strain DA70500]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=904475 SGW63_RS12235 WP_001017133.1 2449778..2450821(+) (vraS) [Staphylococcus aureus strain DA70500]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAAACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997