Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   CC22TP_RS13420 Genome accession   NZ_AP025177
Coordinates   2689951..2690616 (-) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain TPS6281     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2684951..2695616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CC22TP_RS13400 - 2685416..2685529 (-) 114 WP_217654589.1 hypothetical protein -
  CC22TP_RS13405 (TPS6281TP_25170) - 2686193..2688193 (-) 2001 WP_229346829.1 ABC transporter permease -
  CC22TP_RS13410 (TPS6281TP_25180) - 2688190..2688945 (-) 756 WP_000923768.1 ABC transporter ATP-binding protein -
  CC22TP_RS13415 (TPS6281TP_25190) braS 2689053..2689940 (-) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  CC22TP_RS13420 (TPS6281TP_25200) braR 2689951..2690616 (-) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  CC22TP_RS13425 (TPS6281TP_25210) - 2690642..2690842 (-) 201 WP_000604723.1 hypothetical protein -
  CC22TP_RS13430 (TPS6281TP_25220) - 2691040..2692464 (+) 1425 WP_000953731.1 alkaline phosphatase -
  CC22TP_RS14095 - 2692524..2692625 (-) 102 WP_000731972.1 SE2200 family small protein -
  CC22TP_RS13440 (TPS6281TP_25230) - 2692747..2693202 (-) 456 WP_000106184.1 MarR family winged helix-turn-helix transcriptional regulator -
  CC22TP_RS13445 (TPS6281TP_25240) - 2693448..2694209 (-) 762 WP_000323451.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=90341 CC22TP_RS13420 WP_000697883.1 2689951..2690616(-) (braR) [Staphylococcus aureus strain TPS6281]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=90341 CC22TP_RS13420 WP_000697883.1 2689951..2690616(-) (braR) [Staphylococcus aureus strain TPS6281]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACGGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGACAATACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATTATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment