Detailed information NTG0090340

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CC22TP_RS13415
• Genome accession: NZ_AP025177
• Coordinates: 2689053..2689940 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain TPS6281
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2684053..2694940

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CC22TP_RS13385	-	2684071..2684159 (+)	89	Protein_2602	hypothetical protein	-
CC22TP_RS13390 (TPS6281TP_25150)	-	2684267..2684764 (-)	498	WP_001065267.1	glutathione peroxidase	-
CC22TP_RS13395 (TPS6281TP_25160)	-	2684774..2685034 (-)	261	WP_072434822.1	hypothetical protein	-
CC22TP_RS13400	-	2685416..2685529 (-)	114	WP_217654589.1	hypothetical protein	-
CC22TP_RS13405 (TPS6281TP_25170)	-	2686193..2688193 (-)	2001	WP_229346829.1	ABC transporter permease	-
CC22TP_RS13410 (TPS6281TP_25180)	-	2688190..2688945 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
CC22TP_RS13415 (TPS6281TP_25190)	braS	2689053..2689940 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CC22TP_RS13420 (TPS6281TP_25200)	braR	2689951..2690616 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CC22TP_RS13425 (TPS6281TP_25210)	-	2690642..2690842 (-)	201	WP_000604723.1	hypothetical protein	-
CC22TP_RS13430 (TPS6281TP_25220)	-	2691040..2692464 (+)	1425	WP_000953731.1	alkaline phosphatase	-
CC22TP_RS14095	-	2692524..2692625 (-)	102	WP_000731972.1	SE2200 family small protein	-
CC22TP_RS13440 (TPS6281TP_25230)	-	2692747..2693202 (-)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
CC22TP_RS13445 (TPS6281TP_25240)	-	2693448..2694209 (-)	762	WP_000323451.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=90340 CC22TP_RS13415 WP_000143420.1 2689053..2689940(-) (braS) [Staphylococcus aureus strain TPS6281]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=90340 CC22TP_RS13415 WP_000143420.1 2689053..2689940(-) (braS) [Staphylococcus aureus strain TPS6281]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993