Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CC22TP_RS02385 Genome accession   NZ_AP025177
Coordinates   520812..521381 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TPS6281     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 515812..526381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CC22TP_RS02360 (TPS6281TP_04310) cysE 517025..517672 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  CC22TP_RS02365 (TPS6281TP_04320) cysS 517656..519056 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  CC22TP_RS02370 (TPS6281TP_04330) - 519049..519453 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  CC22TP_RS02375 (TPS6281TP_04340) rlmB 519461..520207 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CC22TP_RS02380 (TPS6281TP_04350) - 520207..520731 (+) 525 WP_000664732.1 NYN domain-containing protein -
  CC22TP_RS02385 (TPS6281TP_04360) sigH 520812..521381 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  CC22TP_RS02390 rpmG 521496..521639 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  CC22TP_RS02395 (TPS6281TP_04370) secE 521695..521877 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  CC22TP_RS02400 (TPS6281TP_04380) nusG 521890..522438 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  CC22TP_RS02405 (TPS6281TP_04390) rplK 522619..523041 (+) 423 WP_217654611.1 50S ribosomal protein L11 -
  CC22TP_RS02410 (TPS6281TP_04400) rplA 523249..523941 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  CC22TP_RS02415 (TPS6281TP_04410) rplJ 524213..524713 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  CC22TP_RS02420 (TPS6281TP_04420) rplL 524756..525124 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  CC22TP_RS02425 (TPS6281TP_04430) - 525299..525907 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=90306 CC22TP_RS02385 WP_000872873.1 520812..521381(+) (sigH) [Staphylococcus aureus strain TPS6281]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=90306 CC22TP_RS02385 WP_000872873.1 520812..521381(+) (sigH) [Staphylococcus aureus strain TPS6281]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment