Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABH534_RS08685 Genome accession   NZ_CP157170
Coordinates   1791555..1792211 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 99E2750     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1786555..1797211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABH534_RS08650 (ABH534_08640) dcyD 1787434..1788420 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ABH534_RS08655 (ABH534_08645) tcyL 1788435..1789103 (+) 669 WP_001158206.1 cystine ABC transporter permease -
  ABH534_RS08660 (ABH534_08650) tcyN 1789100..1789852 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABH534_RS08665 (ABH534_08655) sdiA 1790082..1790805 (+) 724 Protein_1686 transcriptional regulator SdiA -
  ABH534_RS08670 (ABH534_08660) yecF 1790872..1791096 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABH534_RS08675 (ABH534_08665) yecU 1791083..1791259 (-) 177 WP_000590347.1 protein YecU -
  ABH534_RS08680 (ABH534_08670) - 1791342..1791413 (-) 72 Protein_1689 transcriptional regulator -
  ABH534_RS08685 (ABH534_08675) letA 1791555..1792211 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABH534_RS08690 (ABH534_08680) uvrC 1792208..1794040 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  ABH534_RS08695 (ABH534_08685) pgsA 1794097..1794645 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABH534_RS08715 (ABH534_08705) - 1795640..1795921 (+) 282 WP_071529678.1 hypothetical protein -
  ABH534_RS08720 (ABH534_08710) - 1796111..1796251 (-) 141 WP_000078920.1 Hok/Gef family protein -
  ABH534_RS08725 (ABH534_08715) - 1796441..1796701 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=902839 ABH534_RS08685 WP_000611335.1 1791555..1792211(+) (letA) [Escherichia coli strain 99E2750]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=902839 ABH534_RS08685 WP_000611335.1 1791555..1792211(+) (letA) [Escherichia coli strain 99E2750]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486