Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABH549_RS11110 Genome accession   NZ_CP157165
Coordinates   2215371..2216027 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain UTAK-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2210371..2221027
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABH549_RS11080 (ABH549_11070) dcyD 2211250..2212236 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  ABH549_RS11085 (ABH549_11075) tcyL 2212251..2212919 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ABH549_RS11090 (ABH549_11080) tcyN 2212916..2213668 (+) 753 WP_095794696.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABH549_RS11095 (ABH549_11085) sdiA 2213898..2214620 (+) 723 WP_033873433.1 transcriptional regulator SdiA -
  ABH549_RS11100 (ABH549_11090) yecF 2214688..2214912 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABH549_RS11105 (ABH549_11095) yecU 2214899..2215075 (-) 177 WP_000590345.1 protein YecU -
  ABH549_RS11110 (ABH549_11100) letA 2215371..2216027 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABH549_RS11115 (ABH549_11105) uvrC 2216024..2217856 (+) 1833 WP_001283426.1 excinuclease ABC subunit UvrC Machinery gene
  ABH549_RS11120 (ABH549_11110) pgsA 2217913..2218461 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABH549_RS11140 (ABH549_11130) yecA 2219110..2219775 (+) 666 WP_062893573.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=902764 ABH549_RS11110 WP_000611328.1 2215371..2216027(+) (letA) [Escherichia coli strain UTAK-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=902764 ABH549_RS11110 WP_000611328.1 2215371..2216027(+) (letA) [Escherichia coli strain UTAK-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCCGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482