Detailed information NTG0899739

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: R6Y88_RS13890
• Genome accession: NZ_CP137687
• Coordinates: 2748064..2749221 (+)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain YT-4
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2743064..2754221

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R6Y88_RS13870	tuaH	2743532..2744725 (+)	1194	WP_080030751.1	teichuronic acid biosynthesis protein TuaH	-
R6Y88_RS13875	tagO	2744870..2745946 (+)	1077	WP_003227975.1	MraY family glycosyltransferase	-
R6Y88_RS13880	tagV	2746019..2747194 (-)	1176	WP_015251114.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
R6Y88_RS13885	yvyE	2747194..2747847 (-)	654	WP_003227979.1	YigZ family protein	-
R6Y88_RS13890	degS	2748064..2749221 (+)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
R6Y88_RS13895	degU	2749304..2749993 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
R6Y88_RS13900	fakBA	2750091..2750936 (+)	846	WP_003227986.1	DegV family protein	-
R6Y88_RS13905	comFA	2751042..2752433 (+)	1392	WP_015384785.1	ATP-dependent helicase ComFA	Machinery gene
R6Y88_RS13910	comFB	2752493..2752789 (+)	297	WP_015483764.1	late competence protein ComFB	-
R6Y88_RS13915	comFC	2752753..2753475 (+)	723	WP_015384784.1	comF operon protein ComFC	Machinery gene
R6Y88_RS13920	yvyF	2753549..2753968 (+)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=899739 R6Y88_RS13890 WP_003227983.1 2748064..2749221(+) (degS) [Bacillus subtilis strain YT-4]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=899739 R6Y88_RS13890 WP_003227983.1 2748064..2749221(+) (degS) [Bacillus subtilis strain YT-4]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATTGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAGATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1