Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   ABC807_RS10040 Genome accession   NZ_CP156625
Coordinates   1946246..1946686 (+) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain TL7/1993     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1941246..1951686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC807_RS10015 (ABC807_10015) ribE 1941288..1941923 (+) 636 WP_000493842.1 riboflavin synthase -
  ABC807_RS10020 (ABC807_10020) - 1941943..1943148 (+) 1206 WP_001818099.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  ABC807_RS10025 (ABC807_10025) ribE 1943149..1943616 (+) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  ABC807_RS10030 (ABC807_10030) hexB 1943941..1945890 (-) 1950 WP_000018169.1 DNA mismatch repair endonuclease MutL Machinery gene
  ABC807_RS10035 (ABC807_10035) - 1946033..1946158 (+) 126 WP_001813544.1 hypothetical protein -
  ABC807_RS10040 (ABC807_10040) brsR 1946246..1946686 (+) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  ABC807_RS10045 (ABC807_10045) - 1946683..1947141 (+) 459 WP_000745054.1 DUF3021 domain-containing protein -
  ABC807_RS10050 (ABC807_10050) - 1947451..1948713 (+) 1263 WP_000075793.1 NRAMP family divalent metal transporter -
  ABC807_RS10055 (ABC807_10055) nrdI 1949006..1949476 (-) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  ABC807_RS10060 (ABC807_10060) - 1949554..1950087 (-) 534 WP_000729029.1 hypothetical protein -
  ABC807_RS10065 (ABC807_10065) - 1950139..1951425 (-) 1287 WP_000278878.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=899735 ABC807_RS10040 WP_000861956.1 1946246..1946686(+) (brsR) [Streptococcus pneumoniae strain TL7/1993]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=899735 ABC807_RS10040 WP_000861956.1 1946246..1946686(+) (brsR) [Streptococcus pneumoniae strain TL7/1993]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363