Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABDE81_RS09570 Genome accession   NZ_CP155555
Coordinates   1995803..1996459 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain LZHX12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1990803..2001459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABDE81_RS09535 dcyD 1991682..1992668 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ABDE81_RS09540 tcyL 1992683..1993351 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ABDE81_RS09545 tcyN 1993348..1994100 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABDE81_RS09550 sdiA 1994330..1995052 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  ABDE81_RS09555 yecF 1995120..1995344 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABDE81_RS09560 yecU 1995331..1995507 (-) 177 WP_000590344.1 protein YecU -
  ABDE81_RS09565 - 1995545..1995661 (-) 117 WP_001302039.1 hypothetical protein -
  ABDE81_RS09570 letA 1995803..1996459 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABDE81_RS09575 uvrC 1996456..1998288 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ABDE81_RS09580 pgsA 1998345..1998893 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABDE81_RS09600 yecA 1999543..2000208 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=897517 ABDE81_RS09570 WP_000611335.1 1995803..1996459(+) (letA) [Escherichia coli strain LZHX12]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=897517 ABDE81_RS09570 WP_000611335.1 1995803..1996459(+) (letA) [Escherichia coli strain LZHX12]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486