Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   LDM87_RS04515 Genome accession   NZ_AP024964
Coordinates   950767..952551 (+) Length   594 a.a.
NCBI ID   WP_223892598.1    Uniprot ID   -
Organism   Helicobacter pylori strain #6     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 945767..957551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDM87_RS04485 (OHP006_08930) motB 946431..947198 (+) 768 WP_001085307.1 flagellar motor protein MotB -
  LDM87_RS04490 (OHP006_08940) - 947202..947639 (+) 438 WP_001031791.1 hypothetical protein -
  LDM87_RS04495 (OHP006_08950) - 947818..949479 (+) 1662 WP_223892595.1 ABC transporter permease/substrate-binding protein -
  LDM87_RS04500 (OHP006_08960) - 949481..950122 (+) 642 WP_223892596.1 ATP-binding cassette domain-containing protein -
  LDM87_RS04505 - 950134..950313 (-) 180 WP_000468796.1 hypothetical protein -
  LDM87_RS04510 (OHP006_08970) - 950305..950766 (+) 462 WP_223892597.1 hypothetical protein -
  LDM87_RS04515 (OHP006_08980) uvrC 950767..952551 (+) 1785 WP_223892598.1 excinuclease ABC subunit UvrC Machinery gene
  LDM87_RS04520 (OHP006_08990) - 952562..953827 (+) 1266 WP_223892599.1 homoserine dehydrogenase -
  LDM87_RS04525 (OHP006_09000) - 953828..954172 (+) 345 WP_001211650.1 YraN family protein -
  LDM87_RS04530 (OHP006_09010) trxA 954261..954581 (+) 321 WP_000020200.1 thioredoxin -
  LDM87_RS04535 (OHP006_09020) trxB 954587..955522 (+) 936 WP_000564370.1 thioredoxin-disulfide reductase -
  LDM87_RS04540 (OHP006_09030) - 955689..956501 (+) 813 WP_212889555.1 glycosyltransferase family 25 protein -
  LDM87_RS04545 (OHP006_09040) - 956696..956944 (-) 249 WP_000790556.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68736.95 Da        Isoelectric Point: 9.5679

>NTDB_id=89734 LDM87_RS04515 WP_223892598.1 950767..952551(+) (uvrC) [Helicobacter pylori strain #6]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHCASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKECLEMIENKDKLIKELELKMEHLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTYNEDLILEEARSLFKLECMPYRVEIFDA
SHHANGQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=89734 LDM87_RS04515 WP_223892598.1 950767..952551(+) (uvrC) [Helicobacter pylori strain #6]
ATGGCTGATTTATTGTCCAGTTTAAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ATCATTGCGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAATGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAGCTCAAACCCAAATACAACATTCTTTTGAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGACATTTTAGACAGCTTATATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCACCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCAATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTATA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAGATCTTTGATGCA
AGCCACCATGCCAACGGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGGAGGGCTTTAGATTTTAATAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACACCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968

Multiple sequence alignment