Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ABC814_RS02980 Genome accession   NZ_CP155533
Coordinates   576087..577931 (+) Length   614 a.a.
NCBI ID   WP_083973716.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Spn1439-106     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 571087..582931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC814_RS02960 (ABC814_02960) - 571919..572698 (+) 780 WP_000290016.1 alpha/beta hydrolase family protein -
  ABC814_RS02965 (ABC814_02965) murM 572810..574030 (+) 1221 WP_001844704.1 peptidoglycan bridge formation alanyltransferase MurM -
  ABC814_RS02970 (ABC814_02970) murN 574035..575267 (+) 1233 WP_083973717.1 peptidoglycan bridge formation alanyltransferase MurN -
  ABC814_RS02975 (ABC814_02975) - 575346..576047 (+) 702 WP_001267410.1 M57 family metalloprotease -
  ABC814_RS02980 (ABC814_02980) uvrC 576087..577931 (+) 1845 WP_083973716.1 excinuclease ABC subunit UvrC Machinery gene
  ABC814_RS02985 (ABC814_02985) - 577921..578754 (+) 834 WP_025169383.1 metallophosphoesterase family protein -
  ABC814_RS02990 (ABC814_02990) - 578936..579736 (-) 801 WP_000714619.1 amino acid ABC transporter substrate-binding protein -
  ABC814_RS02995 (ABC814_02995) - 579907..580512 (+) 606 WP_000670173.1 nitroreductase family protein -
  ABC814_RS03000 (ABC814_03000) pepV 580525..581925 (+) 1401 WP_000560282.1 dipeptidase PepV -
  ABC814_RS03005 (ABC814_03005) - 581979..582557 (+) 579 WP_000078143.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70378.93 Da        Isoelectric Point: 9.3064

>NTDB_id=896785 ABC814_RS02980 WP_083973716.1 576087..577931(+) (uvrC) [Streptococcus pneumoniae strain Spn1439-106]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPSSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGHDDKIIDDLKSKMAVAAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDSKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEAHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNKP

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=896785 ABC814_RS02980 WP_083973716.1 576087..577931(+) (uvrC) [Streptococcus pneumoniae strain Spn1439-106]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATCAAC
CTGATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCCTATCCTTTCATCAAAATCACCAATGA
GCGCTATCCACGCTTGATTATCACTCGTCAGGTCAAAAAGGACGGAGGTCTTTATTTTGGACCTTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGACTTCTAGATAGGATTTTCCCTTTTCGAAAATGTACCAACCCGTCCTCTAAGGTTTGTTTT
TATTACCATATCGGCCAGTGTATGGCCCACACCATCTGTAAGAAGGATGAGGCTTATTTCAAGTCTATGGCTCAGGAGGT
GTCTGATTTTCTGAAAGGTCATGATGACAAAATCATCGATGATCTCAAGAGTAAAATGGCAGTAGCAGCACAAAGTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCGAAA
GATTTGCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAGGG
TAAGCTTATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTTTTGACCTATGTAGGACAAT
TCTATCAAGAAAAATCTCATCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAGGCTGTCAAGGCCTTG
GTGGATTCCAAGATTCTTAAGCCTCAACGTGGAGAGAAAAAACAACTGGTCAATCTAGCCATAAAAAATGCTCGTGTTAG
TCTAGAGCAGAAGTTCAATCTGCTAGAAAAATCTGTCGAAAAGACTCAAGGAGCTATTGAAAATCTAGGGCGTTTGCTCC
AAATCCCGACCCCAGTACGTATCGAGTCCTTCGATAACTCTAATATCATGGGAACTAGCCCTGTTTCGGCTATGGTGGTC
TTTGTCAACGGCAAGCCTAGTAAGAAGGATTACCGTAAGTATAAAATCAAGACCGTAGTCGGGCCAGACGACTATGCCAG
TATGCGAGAGGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATTGCTAAGCAAGTCATCCAAGAAGAACTGGGCTTGGATATTCCAATTGCAGGTCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTGGAAGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGCGCACCGCTTTGCCATCACCTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTTATGAAGCATTTCAAGTCTTTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGGGTACCTAGAGTCGTTGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGGAGAAGCCTTGCCTCAAGTAGCAGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATAAAC
CATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

99.349

100

0.993
  uvrC Streptococcus pneumoniae R6

98.86

100

0.989
  uvrC Streptococcus pneumoniae D39

98.86

100

0.989