Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABC814_RS01970 Genome accession   NZ_CP155533
Coordinates   374801..375433 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain Spn1439-106     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 369801..380433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC814_RS01945 (ABC814_01945) mvaD 370078..371031 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  ABC814_RS01950 (ABC814_01950) - 371018..372025 (+) 1008 WP_000562380.1 phosphomevalonate kinase -
  ABC814_RS01955 (ABC814_01955) fni 372009..373019 (+) 1011 WP_000210619.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ABC814_RS01960 (ABC814_01960) liaF 373097..373795 (+) 699 WP_001224633.1 cell wall-active antibiotics response protein LiaF -
  ABC814_RS01965 (ABC814_01965) - 373792..374787 (+) 996 WP_000743668.1 sensor histidine kinase -
  ABC814_RS01970 (ABC814_01970) vraR 374801..375433 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  ABC814_RS01975 (ABC814_01975) - 375509..376192 (+) 684 Protein_386 DNA alkylation repair protein -
  ABC814_RS01980 (ABC814_01980) - 376342..376581 (+) 240 WP_000754501.1 hypothetical protein -
  ABC814_RS01985 (ABC814_01985) cbpG 376662..377487 (+) 826 Protein_388 choline-binding protein CbpG -
  ABC814_RS01990 (ABC814_01990) cbpF 377506..378528 (+) 1023 WP_050210507.1 choline-binding protein CbpF -
  ABC814_RS01995 (ABC814_01995) - 378656..379892 (-) 1237 Protein_390 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=896773 ABC814_RS01970 WP_000698434.1 374801..375433(+) (vraR) [Streptococcus pneumoniae strain Spn1439-106]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=896773 ABC814_RS01970 WP_000698434.1 374801..375433(+) (vraR) [Streptococcus pneumoniae strain Spn1439-106]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATCTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGTGATCGTACCCAGGCGGCTGTCTACGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41