Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABC810_RS09280 Genome accession   NZ_CP155532
Coordinates   1837810..1838442 (-) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain SP264     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1832810..1843442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC810_RS09255 (ABC810_09245) - 1833228..1834576 (+) 1349 Protein_1785 IS3 family transposase -
  ABC810_RS09260 (ABC810_09260) cbpF 1834704..1835730 (-) 1027 Protein_1786 choline-binding protein CbpF -
  ABC810_RS09265 (ABC810_09265) cbpG 1835749..1836570 (-) 822 WP_001100142.1 choline-binding protein CbpG -
  ABC810_RS09270 (ABC810_09270) - 1836651..1836890 (-) 240 WP_000754501.1 hypothetical protein -
  ABC810_RS09275 (ABC810_09275) - 1837040..1837809 (-) 770 Protein_1789 DNA alkylation repair protein -
  ABC810_RS09280 (ABC810_09285) vraR 1837810..1838442 (-) 633 WP_000698434.1 response regulator transcription factor Regulator
  ABC810_RS09285 (ABC810_09290) - 1838456..1839451 (-) 996 WP_000743674.1 sensor histidine kinase -
  ABC810_RS09290 (ABC810_09295) liaF 1839448..1840146 (-) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  ABC810_RS09295 (ABC810_09300) fni 1840223..1841233 (-) 1011 WP_000210618.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ABC810_RS09300 (ABC810_09305) - 1841217..1842224 (-) 1008 WP_000562413.1 phosphomevalonate kinase -
  ABC810_RS09305 (ABC810_09310) mvaD 1842211..1843164 (-) 954 WP_000373457.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=896739 ABC810_RS09280 WP_000698434.1 1837810..1838442(-) (vraR) [Streptococcus pneumoniae strain SP264]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=896739 ABC810_RS09280 WP_000698434.1 1837810..1838442(-) (vraR) [Streptococcus pneumoniae strain SP264]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGAATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41