Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   LDN16_RS03445 Genome accession   NZ_AP024961
Coordinates   725705..727912 (-) Length   735 a.a.
NCBI ID   WP_038837641.1    Uniprot ID   A0A4T1FFX4
Organism   Legionella pneumophila strain 80-045     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 720705..732912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDN16_RS03425 - 721210..723138 (-) 1929 WP_161505073.1 hypothetical protein -
  LDN16_RS03430 (LEG80045_06520) - 723264..723656 (-) 393 WP_011214843.1 hypothetical protein -
  LDN16_RS03435 (LEG80045_06530) - 723793..724170 (+) 378 WP_038837636.1 hypothetical protein -
  LDN16_RS03440 (LEG80045_06540) - 724372..725679 (+) 1308 WP_161514101.1 tetratricopeptide repeat protein -
  LDN16_RS03445 (LEG80045_06550) comEC 725705..727912 (-) 2208 WP_038837641.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LDN16_RS03450 (LEG80045_06560) pilE 727990..728439 (-) 450 WP_010946364.1 type IV pilin protein Machinery gene
  LDN16_RS03455 (LEG80045_06570) - 728451..731960 (-) 3510 WP_161504147.1 pilus assembly protein -
  LDN16_RS03460 (LEG80045_06580) - 731973..732485 (-) 513 WP_027219362.1 pilus assembly protein -

Sequence

Protein


Download         Length: 735 a.a.        Molecular weight: 83196.74 Da        Isoelectric Point: 9.6732

>NTDB_id=89645 LDN16_RS03445 WP_038837641.1 725705..727912(-) (comEC) [Legionella pneumophila strain 80-045]
MEIFCFLIGVLYAYTYNIYLTIAIPLLFYITPRYPIVLFFIAGCGFALIHQWIVSPKGMPDTQVITQAQLEGTIASIPMQ
RPNKTQFHFAIEKINNNPAQGLIQLNWYNKPPVLRAGQRWQLSVKLKKPRNFHNPGGFNYVSYLGARHIHWTGYIRYGNN
KLISNQPPSFSWLTLREKIGDALTKMAPNTETAGIIEALTLNVTHHISSDHWNLFRRTGTIHLFGISGEHIALVSGIFFI
VMRWIWSINYRCCLFLPANTIASIGGLLAALPYSFLAGFEPPVQRALIGCVLYTIYAIGKQRFTPWQIWRYALFLVLCIE
PHAVFLQGFYFSFLAVACLLLTHQRWPLKNYKKTLALQLSCLIGLMPLTLHWYSYGSINGFLANLFAIPLVSFLIVPLAL
MTMITSPFHWSWILMKPLAWLVALLLQGLTYVEQIAGINITWSITSVTMMLAMTAGLFLRVLLPVKPFKHLAILWIILPL
FPPRTAIYPGEALINILDVGQGLAVAIQTQHHVLLYDTGDSYFQGSDLGQMAIIPFFRSIGIKTIDKIVISHPDKDHKGG
LNSLEKEMQVNQLIVNDPYFYKRGSNCHSYPQWQWDGVSFRFLPIRESFNKKNNNSCILQVSNSAGRVLLTGDIEKAAEE
YLVRNYGSQLASEILVVPHHGSKTSSSYRFLLEVSPLYAIASLGFDNRFKFPHSKTLQSMKTLGITFFRTDECGMAEIKL
PASGKINKPTCMQAE

Nucleotide


Download         Length: 2208 bp        

>NTDB_id=89645 LDN16_RS03445 WP_038837641.1 725705..727912(-) (comEC) [Legionella pneumophila strain 80-045]
ATGGAAATTTTTTGCTTTTTAATAGGCGTACTTTATGCCTATACCTATAATATTTATCTAACTATTGCGATTCCTTTACT
CTTTTATATCACCCCAAGGTATCCGATTGTCCTGTTCTTCATCGCCGGGTGCGGCTTTGCCCTGATTCATCAGTGGATTG
TATCTCCCAAGGGCATGCCTGATACGCAAGTAATCACTCAAGCCCAATTGGAAGGAACTATTGCGTCCATCCCCATGCAA
CGTCCTAACAAAACCCAATTCCATTTTGCAATTGAAAAAATTAATAATAACCCTGCTCAAGGCTTGATCCAATTAAACTG
GTATAACAAACCACCTGTCTTACGAGCCGGTCAGCGATGGCAACTTTCAGTGAAACTAAAAAAACCTCGTAACTTCCACA
ACCCGGGAGGTTTTAATTATGTAAGTTACCTGGGGGCTCGTCATATCCATTGGACTGGCTATATTCGTTATGGGAATAAT
AAGCTAATTAGCAATCAACCCCCTTCTTTCAGTTGGTTAACACTACGTGAAAAAATTGGGGATGCTTTGACAAAAATGGC
ACCGAATACAGAAACGGCGGGCATCATCGAAGCATTGACGTTAAATGTTACTCACCATATCAGTTCAGATCATTGGAATT
TGTTCCGAAGAACAGGAACGATACATTTATTCGGCATTTCAGGAGAACACATCGCTCTGGTCTCCGGCATTTTCTTTATC
GTGATGAGATGGATTTGGTCAATAAATTATCGATGCTGTTTGTTCTTACCGGCCAATACCATAGCGAGTATCGGTGGGCT
ACTGGCCGCCTTGCCCTATTCTTTTTTAGCCGGGTTTGAGCCTCCTGTGCAACGTGCTTTAATTGGTTGTGTACTTTACA
CAATATACGCCATAGGAAAACAACGTTTTACACCATGGCAAATATGGAGATATGCCTTATTTTTAGTCTTGTGTATTGAG
CCCCATGCCGTATTCCTGCAAGGTTTTTACTTTTCATTTCTTGCCGTGGCCTGTCTTCTATTGACTCATCAACGCTGGCC
ACTGAAAAATTATAAAAAAACACTGGCATTACAATTAAGCTGCCTCATTGGATTAATGCCCTTGACTCTCCATTGGTACT
CCTATGGTTCTATCAATGGATTTCTTGCCAATTTATTCGCCATACCTTTAGTCAGTTTTCTGATAGTGCCCTTGGCTTTA
ATGACTATGATAACGAGTCCATTTCATTGGTCCTGGATATTGATGAAACCATTGGCGTGGCTTGTTGCCCTGTTACTGCA
AGGACTAACGTATGTTGAGCAAATAGCTGGGATCAATATCACCTGGTCCATCACCTCGGTAACAATGATGCTCGCTATGA
CAGCAGGTCTGTTTTTAAGGGTATTATTACCCGTCAAGCCATTCAAACACTTGGCTATCCTTTGGATTATCCTTCCCTTA
TTTCCGCCTCGTACTGCAATTTATCCAGGGGAAGCATTAATTAATATTTTGGATGTTGGGCAAGGACTTGCCGTTGCGAT
ACAAACGCAACATCATGTTTTACTCTACGATACGGGAGATTCCTATTTTCAGGGAAGTGATTTAGGGCAAATGGCGATAA
TCCCCTTTTTCAGGTCAATTGGAATAAAAACAATTGACAAAATAGTAATAAGCCATCCCGATAAAGATCATAAAGGCGGA
TTAAATTCCCTTGAAAAAGAGATGCAAGTTAATCAACTAATAGTGAATGATCCCTATTTTTATAAACGTGGAAGTAATTG
TCATTCATACCCGCAATGGCAATGGGATGGGGTGAGTTTTCGTTTTTTACCCATCAGGGAATCTTTCAATAAAAAAAATA
ATAATTCTTGTATCTTGCAGGTAAGTAATTCGGCTGGCAGGGTTTTATTAACGGGAGATATTGAAAAAGCAGCGGAGGAG
TACCTGGTAAGAAACTACGGCAGTCAGCTGGCATCAGAAATTTTAGTTGTGCCTCATCATGGGAGCAAAACGTCTTCATC
CTATCGATTTTTGCTGGAAGTAAGTCCGCTTTATGCCATTGCATCTTTAGGATTTGATAATCGCTTCAAATTTCCACATT
CTAAAACTTTGCAAAGCATGAAAACATTAGGTATCACTTTTTTTAGAACAGACGAATGCGGAATGGCAGAAATCAAACTA
CCTGCGTCAGGTAAAATTAACAAACCAACCTGTATGCAGGCTGAATAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(21-158)

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-578)

Competence protein (Competence)

(199-464)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4T1FFX4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Legionella pneumophila strain Lp02

98.501

99.864

0.984
  comEC Legionella pneumophila strain ERS1305867

96.599

100

0.966

Multiple sequence alignment