Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4705_RS07215 Genome accession   NZ_CP137115
Coordinates   1366579..1367268 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20614-6     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1361579..1372268
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4705_RS07190 gpsB 1361688..1362017 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R4705_RS07200 - 1362503..1363660 (+) 1158 WP_000711393.1 class I SAM-dependent RNA methyltransferase -
  R4705_RS07205 mapZ 1363673..1365067 (+) 1395 WP_050076091.1 mid-cell-anchored protein MapZ -
  R4705_RS07210 gndA 1365143..1366567 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  R4705_RS07215 covR 1366579..1367268 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  R4705_RS07220 cbpC 1367366..1368388 (+) 1023 WP_268221865.1 choline-binding protein CbpC -
  R4705_RS07225 - 1368407..1369528 (+) 1122 WP_000771140.1 N-acetylmuramoyl-L-alanine amidase family protein -
  R4705_RS07230 - 1369646..1370878 (-) 1233 WP_000765691.1 MFS transporter -
  R4705_RS07235 - 1370921..1371796 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=896281 R4705_RS07215 WP_000518011.1 1366579..1367268(+) (covR) [Streptococcus pneumoniae strain 20614-6]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=896281 R4705_RS07215 WP_000518011.1 1366579..1367268(+) (covR) [Streptococcus pneumoniae strain 20614-6]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467