Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R4705_RS03930 Genome accession   NZ_CP137115
Coordinates   733162..733782 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain 20614-6     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 728162..738782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4705_RS03905 recA 728540..729706 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  R4705_RS03910 cinA 729761..731017 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  R4705_RS03915 brpA 731101..732117 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  R4705_RS03920 - 732125..732643 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  R4705_RS03925 tsaE 732633..733076 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R4705_RS03930 comM 733162..733782 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R4705_RS03935 - 734165..735028 (-) 864 Protein_757 helix-turn-helix domain-containing protein -
  R4705_RS03940 - 735217..735387 (+) 171 WP_000742179.1 PhrA family quorum-sensing system peptide -
  R4705_RS03945 - 735837..737852 (+) 2016 WP_279513737.1 DUF1430 domain-containing protein -
  R4705_RS03950 - 737854..738486 (+) 633 WP_000571410.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=896248 R4705_RS03930 WP_000839908.1 733162..733782(-) (comM) [Streptococcus pneumoniae strain 20614-6]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=896248 R4705_RS03930 WP_000839908.1 733162..733782(-) (comM) [Streptococcus pneumoniae strain 20614-6]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369