Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   R4705_RS02040 Genome accession   NZ_CP137115
Coordinates   388911..390143 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae strain 20614-6     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 383911..395143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4705_RS02010 - 384098..385066 (+) 969 WP_000080999.1 NAD(P)/FAD-dependent oxidoreductase -
  R4705_RS02015 whiA 385100..386011 (-) 912 WP_050084141.1 DNA-binding protein WhiA -
  R4705_RS02020 - 386008..386985 (-) 978 WP_001231069.1 YvcK family protein -
  R4705_RS02025 rapZ 386982..387872 (-) 891 WP_000163029.1 RNase adapter RapZ -
  R4705_RS02030 - 387924..388304 (-) 381 WP_001140412.1 RidA family protein -
  R4705_RS02035 yihA 388315..388902 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  R4705_RS02040 clpX 388911..390143 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  R4705_RS02045 - 390175..390345 (-) 171 WP_000442275.1 hypothetical protein -
  R4705_RS02050 - 390345..390851 (-) 507 WP_000162482.1 dihydrofolate reductase -
  R4705_RS02055 - 390981..391499 (-) 519 WP_000229874.1 DNA starvation/stationary phase protection protein -
  R4705_RS02060 - 391995..393317 (-) 1323 Protein_406 GH25 family lysozyme -
  R4705_RS02065 tpiA 393355..394113 (-) 759 WP_000087896.1 triose-phosphate isomerase -
  R4705_RS02070 - 394210..394887 (-) 678 WP_000221614.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=896232 R4705_RS02040 WP_000106346.1 388911..390143(-) (clpX) [Streptococcus pneumoniae strain 20614-6]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=896232 R4705_RS02040 WP_000106346.1 388911..390143(-) (clpX) [Streptococcus pneumoniae strain 20614-6]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATTGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATTGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561