Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R4701_RS06855 Genome accession   NZ_CP137114
Coordinates   1349041..1349661 (+) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain 15P3054     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1344041..1354661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS06830 - 1344223..1344501 (-) 279 WP_317805817.1 competence protein ComA -
  R4701_RS06835 - 1344642..1345274 (-) 633 WP_000571426.1 ABC transporter ATP-binding protein -
  R4701_RS06840 - 1345276..1347291 (-) 2016 WP_000732396.1 DUF1430 domain-containing protein -
  R4701_RS06845 - 1347436..1347606 (-) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  R4701_RS06850 - 1347795..1348658 (+) 864 WP_001093619.1 helix-turn-helix domain-containing protein -
  R4701_RS06855 comM 1349041..1349661 (+) 621 WP_000839908.1 hypothetical protein Regulator
  R4701_RS06860 tsaE 1349748..1350191 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R4701_RS06865 - 1350181..1350699 (+) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  R4701_RS06870 brpA 1350707..1351723 (+) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  R4701_RS06875 cinA 1351808..1353064 (+) 1257 WP_000642705.1 competence/damage-inducible protein A Machinery gene
  R4701_RS06880 recA 1353119..1354285 (+) 1167 WP_001085463.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=896197 R4701_RS06855 WP_000839908.1 1349041..1349661(+) (comM) [Streptococcus pneumoniae strain 15P3054]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=896197 R4701_RS06855 WP_000839908.1 1349041..1349661(+) (comM) [Streptococcus pneumoniae strain 15P3054]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTGGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369