Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4701_RS03380 Genome accession   NZ_CP137114
Coordinates   671837..672526 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P3054     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 666837..677526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS03355 - 667530..667859 (-) 330 WP_000196977.1 transposase -
  R4701_RS03360 - 668471..668860 (+) 390 WP_001865604.1 lanthionine synthetase LanC family protein -
  R4701_RS03365 - 668760..669347 (+) 588 WP_001822134.1 lanthionine synthetase LanC family protein -
  R4701_RS03370 - 669390..670622 (+) 1233 WP_000765676.1 MFS transporter -
  R4701_RS03375 cbpJ 670740..671738 (-) 999 WP_317805985.1 choline-binding protein CbpJ -
  R4701_RS03380 covR 671837..672526 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  R4701_RS03385 gndA 672538..673962 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  R4701_RS03390 mapZ 674038..675432 (-) 1395 WP_000039275.1 mid-cell-anchored protein MapZ -
  R4701_RS03395 - 675445..676602 (-) 1158 WP_000711388.1 class I SAM-dependent RNA methyltransferase -
  R4701_RS03405 gpsB 677088..677417 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=896162 R4701_RS03380 WP_000518011.1 671837..672526(-) (covR) [Streptococcus pneumoniae strain 15P3054]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=896162 R4701_RS03380 WP_000518011.1 671837..672526(-) (covR) [Streptococcus pneumoniae strain 15P3054]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467