Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4707_RS07745 Genome accession   NZ_CP137113
Coordinates   1452281..1452970 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ZGX     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1447281..1457970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS07720 gpsB 1447378..1447719 (+) 342 WP_000200644.1 cell division regulator GpsB -
  R4707_RS07730 - 1448205..1449362 (+) 1158 WP_000711398.1 class I SAM-dependent RNA methyltransferase -
  R4707_RS07735 mapZ 1449375..1450769 (+) 1395 WP_081543039.1 mid-cell-anchored protein MapZ -
  R4707_RS07740 gndA 1450845..1452269 (+) 1425 WP_000158794.1 NADP-dependent phosphogluconate dehydrogenase -
  R4707_RS07745 covR 1452281..1452970 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  R4707_RS07750 cbpC 1453068..1454087 (+) 1020 WP_081543040.1 choline-binding protein CbpC -
  R4707_RS07755 mvk 1454209..1455087 (+) 879 WP_000163329.1 mevalonate kinase -
  R4707_RS07760 mvaD 1455069..1456022 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  R4707_RS07765 - 1456009..1457016 (+) 1008 WP_061364552.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=896129 R4707_RS07745 WP_000518011.1 1452281..1452970(+) (covR) [Streptococcus pneumoniae strain ZGX]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=896129 R4707_RS07745 WP_000518011.1 1452281..1452970(+) (covR) [Streptococcus pneumoniae strain ZGX]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467