Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R4707_RS04150 Genome accession   NZ_CP137113
Coordinates   772316..772936 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain ZGX     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 767316..777936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS04125 recA 767694..768860 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R4707_RS04130 cinA 768915..770171 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  R4707_RS04135 brpA 770255..771271 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  R4707_RS04140 - 771279..771797 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  R4707_RS04145 tsaE 771787..772230 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R4707_RS04150 comM 772316..772936 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R4707_RS04155 - 773319..774182 (-) 864 WP_001093628.1 helix-turn-helix domain-containing protein -
  R4707_RS04160 - 774370..774539 (+) 170 Protein_802 PhrA family quorum-sensing system peptide -
  R4707_RS04165 - 774854..775150 (+) 297 WP_000911560.1 lactococcin 972 family bacteriocin -
  R4707_RS04170 - 775253..777268 (+) 2016 WP_050072292.1 bacteriocin-associated integral membrane family protein -
  R4707_RS04175 - 777270..777902 (+) 633 WP_050072293.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=896094 R4707_RS04150 WP_000839908.1 772316..772936(-) (comM) [Streptococcus pneumoniae strain ZGX]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=896094 R4707_RS04150 WP_000839908.1 772316..772936(-) (comM) [Streptococcus pneumoniae strain ZGX]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369