Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4706_RS03560 Genome accession   NZ_CP137111
Coordinates   720021..720710 (-) Length   229 a.a.
NCBI ID   WP_000518010.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 17023     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 715021..725710
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS03535 - 715615..716003 (+) 389 Protein_701 lanthionine synthetase LanC family protein -
  R4706_RS03540 - 716071..716523 (+) 453 WP_025173614.1 lanthionine synthetase -
  R4706_RS03545 - 716534..717766 (+) 1233 WP_000765698.1 MFS transporter -
  R4706_RS03550 cbpJ 717884..718882 (-) 999 WP_050198729.1 choline-binding protein CbpJ -
  R4706_RS03555 cbpC 718901..719923 (-) 1023 WP_044727648.1 choline-binding protein CbpC -
  R4706_RS03560 covR 720021..720710 (-) 690 WP_000518010.1 response regulator transcription factor Regulator
  R4706_RS03565 gndA 720722..722146 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  R4706_RS03570 mapZ 722222..723592 (-) 1371 WP_044727647.1 mid-cell-anchored protein MapZ -
  R4706_RS03575 - 723605..724762 (-) 1158 WP_000711402.1 class I SAM-dependent RNA methyltransferase -
  R4706_RS03585 gpsB 725248..725577 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26862.16 Da        Isoelectric Point: 6.9836

>NTDB_id=895931 R4706_RS03560 WP_000518010.1 720021..720710(-) (covR) [Streptococcus pneumoniae strain 17023]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=895931 R4706_RS03560 WP_000518010.1 720021..720710(-) (covR) [Streptococcus pneumoniae strain 17023]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463