Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   R4712_RS10610 Genome accession   NZ_CP137110
Coordinates   2040600..2041409 (+) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain 16H2041     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2035600..2046409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4712_RS10590 - 2037100..2037225 (-) 126 WP_001818232.1 hypothetical protein -
  R4712_RS10595 mutY 2037322..2038497 (+) 1176 WP_000886145.1 A/G-specific adenine glycosylase -
  R4712_RS10600 micA 2038552..2039256 (+) 705 WP_000722076.1 response regulator YycF Regulator
  R4712_RS10605 micB 2039249..2040598 (+) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R4712_RS10610 vicX 2040600..2041409 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  R4712_RS10615 relB 2041500..2041742 (+) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  R4712_RS10620 - 2041744..2041998 (+) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  R4712_RS10625 - 2042045..2042821 (+) 777 WP_044791794.1 potassium channel family protein -
  R4712_RS10630 cpoA 2042982..2044025 (+) 1044 WP_000412280.1 alpha-galactosylglucosyldiacylglycerol synthase -
  R4712_RS10635 - 2044041..2045366 (+) 1326 WP_001219427.1 glycosyltransferase family 4 protein -
  R4712_RS10640 - 2045397..2045573 (+) 177 WP_001256250.1 PspC domain-containing protein -
  R4712_RS10645 - 2045632..2045766 (+) 135 WP_000863859.1 DUF4044 domain-containing protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=895912 R4712_RS10610 WP_001289493.1 2040600..2041409(+) (vicX) [Streptococcus pneumoniae strain 16H2041]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=895912 R4712_RS10610 WP_001289493.1 2040600..2041409(+) (vicX) [Streptococcus pneumoniae strain 16H2041]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTGGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGCAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACTTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGACAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773