Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R4712_RS05435 Genome accession   NZ_CP137110
Coordinates   1071036..1071698 (+) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 16H2041     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1066036..1076698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4712_RS05405 tnpB 1066487..1066810 (+) 324 WP_000586643.1 IS66 family insertion sequence element accessory protein TnpB -
  R4712_RS05410 - 1066951..1067259 (-) 309 Protein_1070 transposase -
  R4712_RS05415 - 1067232..1067770 (+) 539 Protein_1071 transposase -
  R4712_RS05420 cysK 1067845..1068765 (-) 921 WP_000029866.1 cysteine synthase A -
  R4712_RS05425 - 1069050..1069685 (-) 636 WP_000395739.1 YigZ family protein -
  R4712_RS05430 comFA/cflA 1069741..1071039 (+) 1299 WP_000867615.1 DEAD/DEAH box helicase Machinery gene
  R4712_RS05435 comFC/cflB 1071036..1071698 (+) 663 WP_000649971.1 ComF family protein Machinery gene
  R4712_RS05440 hpf 1071778..1072326 (+) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R4712_RS05445 - 1072462..1074435 (+) 1974 WP_000715110.1 DHH family phosphoesterase -
  R4712_RS05450 rplI 1074432..1074884 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  R4712_RS05455 dnaB 1074928..1076280 (+) 1353 WP_000852486.1 replicative DNA helicase -
  R4712_RS05460 - 1076282..1076548 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=895865 R4712_RS05435 WP_000649971.1 1071036..1071698(+) (comFC/cflB) [Streptococcus pneumoniae strain 16H2041]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=895865 R4712_RS05435 WP_000649971.1 1071036..1071698(+) (comFC/cflB) [Streptococcus pneumoniae strain 16H2041]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914