Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   R4711_RS07515 Genome accession   NZ_CP137107
Coordinates   1458697..1459764 (+) Length   355 a.a.
NCBI ID   WP_000159554.1    Uniprot ID   A0A062WMA1
Organism   Streptococcus pneumoniae strain 15H4024     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1453697..1464764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS07500 amiA3 1454220..1456199 (+) 1980 WP_000742232.1 peptide ABC transporter substrate-binding protein Regulator
  R4711_RS07505 amiC 1456266..1457762 (+) 1497 WP_000759902.1 ABC transporter permease Regulator
  R4711_RS07510 amiD 1457762..1458688 (+) 927 WP_000103697.1 oligopeptide ABC transporter permease OppC Regulator
  R4711_RS07515 amiE 1458697..1459764 (+) 1068 WP_000159554.1 ABC transporter ATP-binding protein Regulator
  R4711_RS07520 amiF 1459775..1460701 (+) 927 WP_001291293.1 ATP-binding cassette domain-containing protein Regulator
  R4711_RS07530 treR 1462180..1462890 (-) 711 WP_000760673.1 trehalose operon repressor Regulator

Sequence

Protein


Download         Length: 355 a.a.        Molecular weight: 39490.09 Da        Isoelectric Point: 4.8727

>NTDB_id=895664 R4711_RS07515 WP_000159554.1 1458697..1459764(+) (amiE) [Streptococcus pneumoniae strain 15H4024]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide


Download         Length: 1068 bp        

>NTDB_id=895664 R4711_RS07515 WP_000159554.1 1458697..1459764(+) (amiE) [Streptococcus pneumoniae strain 15H4024]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGATTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-301)

ABC transporter (ABC_tran)

(29-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A062WMA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

88.169

100

0.882
  amiE Streptococcus thermophilus LMG 18311

86.479

100

0.865
  amiE Streptococcus thermophilus LMD-9

86.479

100

0.865
  oppD Streptococcus mutans UA159

54.545

99.155

0.541