Detailed information NTG0895653

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R4711_RS07060
• Genome accession: NZ_CP137107
• Coordinates: 1382898..1383935 (+)
• Length: 345 a.a.
• NCBI ID: WP_050263715.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 15H4024
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1377898..1388935

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4711_RS07025	yidC	1377934..1378860 (-)	927	WP_050263714.1	membrane protein insertase YidC	-
R4711_RS07030	-	1378938..1379216 (-)	279	WP_001174613.1	acylphosphatase	-
R4711_RS07035	-	1379250..1379990 (+)	741	WP_000152678.1	RNA methyltransferase	-
R4711_RS07040	-	1380046..1380729 (+)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
R4711_RS07045	asnA	1380840..1381832 (+)	993	WP_000747993.1	aspartate--ammonia ligase	-
R4711_RS07050	rsmD	1381897..1382436 (+)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R4711_RS07055	coaD	1382426..1382914 (+)	489	WP_044813415.1	pantetheine-phosphate adenylyltransferase	-
R4711_RS07060	sepM	1382898..1383935 (+)	1038	WP_050263715.1	SepM family pheromone-processing serine protease	Regulator
R4711_RS07065	-	1383993..1384223 (+)	231	WP_000250392.1	DUF1146 family protein	-
R4711_RS07070	murA	1384247..1385530 (+)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R4711_RS07075	-	1385523..1385711 (+)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
R4711_RS07080	endA	1385750..1386574 (+)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
R4711_RS07085	-	1386865..1388196 (+)	1332	WP_000390039.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37509.56 Da
• Isoelectric Point: 5.2280

>NTDB_id=895653 R4711_RS07060 WP_050263715.1 1382898..1383935(+) (sepM) [Streptococcus pneumoniae strain 15H4024]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGNSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNSP

Nucleotide

• Length: 1038 bp

>NTDB_id=895653 R4711_RS07060 WP_050263715.1 1382898..1383935(+) (sepM) [Streptococcus pneumoniae strain 15H4024]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGAATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAGTCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60	98.551	0.591