Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R4711_RS07080 Genome accession   NZ_CP137107
Coordinates   1385750..1386574 (+) Length   274 a.a.
NCBI ID   WP_001036779.1    Uniprot ID   P0A3S3
Organism   Streptococcus pneumoniae strain 15H4024     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1380750..1391574
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS07045 asnA 1380840..1381832 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  R4711_RS07050 rsmD 1381897..1382436 (+) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R4711_RS07055 coaD 1382426..1382914 (+) 489 WP_044813415.1 pantetheine-phosphate adenylyltransferase -
  R4711_RS07060 sepM 1382898..1383935 (+) 1038 WP_050263715.1 SepM family pheromone-processing serine protease Regulator
  R4711_RS07065 - 1383993..1384223 (+) 231 WP_000250392.1 DUF1146 family protein -
  R4711_RS07070 murA 1384247..1385530 (+) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R4711_RS07075 - 1385523..1385711 (+) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  R4711_RS07080 endA 1385750..1386574 (+) 825 WP_001036779.1 DNA-entry nuclease EndA Machinery gene
  R4711_RS07085 - 1386865..1388196 (+) 1332 WP_000390039.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29890.57 Da        Isoelectric Point: 10.1197

>NTDB_id=895654 R4711_RS07080 WP_001036779.1 1385750..1386574(+) (endA) [Streptococcus pneumoniae strain 15H4024]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=895654 R4711_RS07080 WP_001036779.1 1385750..1386574(+) (endA) [Streptococcus pneumoniae strain 15H4024]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCCGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3OWV

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

100

100

1
  endA Streptococcus pneumoniae D39

100

100

1
  endA Streptococcus pneumoniae R6

100

100

1
  endA Streptococcus pneumoniae TIGR4

100

100

1