Detailed information NTG0895652

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R4711_RS06910
• Genome accession: NZ_CP137107
• Coordinates: 1356027..1357037 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 15H4024
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1351027..1362037

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4711_RS06880	-	1351899..1352105 (+)	207	Protein_1331	hypothetical protein	-
R4711_RS06885	-	1352102..1352296 (+)	195	WP_000820187.1	hypothetical protein	-
R4711_RS06890	-	1352283..1353167 (+)	885	WP_000219347.1	ABC transporter ATP-binding protein	-
R4711_RS06895	-	1353169..1353906 (+)	738	WP_001809843.1	ABC transporter permease	-
R4711_RS06900	-	1353906..1355003 (+)	1098	WP_000893537.1	sensor histidine kinase	-
R4711_RS06905	-	1355004..1355603 (+)	600	WP_000866698.1	response regulator transcription factor	-
R4711_RS06910	ccpA	1356027..1357037 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
R4711_RS06915	-	1357378..1358340 (-)	963	WP_001124777.1	asparaginase	-
R4711_RS06920	-	1358406..1359794 (+)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
R4711_RS06925	-	1359829..1360281 (-)	453	WP_000079148.1	universal stress protein	-
R4711_RS06930	-	1360443..1360736 (+)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=895652 R4711_RS06910 WP_000990607.1 1356027..1357037(+) (ccpA) [Streptococcus pneumoniae strain 15H4024]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=895652 R4711_RS06910 WP_000990607.1 1356027..1357037(+) (ccpA) [Streptococcus pneumoniae strain 15H4024]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568