Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4711_RS03590 Genome accession   NZ_CP137107
Coordinates   716483..717172 (-) Length   229 a.a.
NCBI ID   WP_000518016.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15H4024     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 711483..722172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS03565 - 712186..712524 (+) 339 WP_001820155.1 lanthionine synthetase LanC family protein -
  R4711_RS03570 - 712424..712894 (+) 471 WP_001810352.1 lanthionine synthetase LanC family protein -
  R4711_RS03575 - 713053..714285 (+) 1233 WP_050263845.1 MFS transporter -
  R4711_RS03580 cbpJ 714403..715401 (-) 999 WP_000771134.1 choline-binding protein CbpJ -
  R4711_RS03585 cbpC 715420..716385 (-) 966 WP_000771105.1 choline-binding protein CbpC -
  R4711_RS03590 covR 716483..717172 (-) 690 WP_000518016.1 response regulator transcription factor Regulator
  R4711_RS03595 gndA 717184..718608 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  R4711_RS03600 mapZ 718684..720078 (-) 1395 WP_000039276.1 mid-cell-anchored protein MapZ -
  R4711_RS03605 - 720091..721248 (-) 1158 WP_000711391.1 class I SAM-dependent RNA methyltransferase -
  R4711_RS03615 gpsB 721734..722063 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26932.24 Da        Isoelectric Point: 6.9836

>NTDB_id=895619 R4711_RS03590 WP_000518016.1 716483..717172(-) (covR) [Streptococcus pneumoniae strain 15H4024]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=895619 R4711_RS03590 WP_000518016.1 716483..717172(-) (covR) [Streptococcus pneumoniae strain 15H4024]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463