Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   R4702_RS00660 Genome accession   NZ_CP137106
Coordinates   137141..138952 (-) Length   603 a.a.
NCBI ID   WP_050205458.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P4028     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 132141..143952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4702_RS00625 - 132255..133097 (+) 843 WP_000954122.1 DUF368 domain-containing protein -
  R4702_RS00630 - 133097..133579 (+) 483 WP_001085888.1 aminoacyl-tRNA deacylase -
  R4702_RS00635 - 133579..134199 (+) 621 WP_000780813.1 histidine phosphatase family protein -
  R4702_RS00640 - 134452..134547 (-) 96 Protein_128 IS630 family transposase -
  R4702_RS00645 - 134960..135301 (+) 342 Protein_129 transposase -
  R4702_RS00650 prsA 135418..136359 (-) 942 WP_000727935.1 peptidylprolyl isomerase PrsA -
  R4702_RS00655 - 136426..137139 (-) 714 WP_000230399.1 O-methyltransferase -
  R4702_RS00660 pepF 137141..138952 (-) 1812 WP_050205458.1 oligoendopeptidase F Regulator
  R4702_RS00665 coiA 138971..139924 (-) 954 WP_317810025.1 competence protein CoiA Machinery gene
  R4702_RS00670 tehB 139997..140857 (-) 861 WP_000413762.1 SAM-dependent methyltransferase TehB -
  R4702_RS00675 smpB 140873..141340 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -
  R4702_RS00680 rnr 141303..143657 (-) 2355 WP_317810027.1 ribonuclease R -

Sequence

Protein


Download         Length: 603 a.a.        Molecular weight: 70310.25 Da        Isoelectric Point: 4.6013

>NTDB_id=895525 R4702_RS00660 WP_050205458.1 137141..138952(-) (pepF) [Streptococcus pneumoniae strain 16P4028]
MVLQRNERNERNEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQMEKLYVYAHM
KNDQDTREAKYQEYYAKAMTLYSQLDQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLKGKDHVLSQREEELL
AGAGEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQTNV
KVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQE
ALKKAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYT
RETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLT
SDFLNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSD
YPLNVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1812 bp        

>NTDB_id=895525 R4702_RS00660 WP_050205458.1 137141..138952(-) (pepF) [Streptococcus pneumoniae strain 16P4028]
ATGGTATTACAAAGAAATGAAAGAAATGAAAGAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCA
GGCTTGGGAAGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCTTGGATAGTG
CGGATAACCTACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATGGAGAAGCTTTACGTTTATGCTCATATG
AAGAATGACCAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCAGTTAGACCA
AGCCTTTTCATTCTATGATCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAGC
TGCAGGTTTATCAACACTATTTTGACAAGCTCTTGAAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAAGAATTATTG
GCTGGAGCTGGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGT
CCTAGACGATGATGGTAAAGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAAACGTGAGGTTC
GCCGTGGTGCCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTT
AAGGTGCAAAATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTTTGTTCCAGA
AAGTGTTTATGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTCGTTCAAAAA
TCTTGGGGATTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAGTTTTACCTACCAAGAA
GCCTTGAAAAAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTTAAACGTGCCTTCAGCGAGCG
TTGGATTGATGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTACGATACCAATGCCTTTATGC
TTCTCAACTGGCAAGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACT
CGTGAAACTCAGCCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGAAAATATCTT
GACGGAGAAATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTG
GAACAGTTTTCCGCCAAACTCAATTTGCTGAGTTTGAACACGCCATTCACCAAGCAGATCAAAATGGGGAGGTCTTGACA
AGCGATTTCCTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCA
ATACGAGTGGGCTCGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACTGGCTTTGCGGCCGCCTCAG
CCTTGGCTGAAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCGGAC
TATCCACTTAATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGA
ACGCCGTTTAAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(205-584)

Oligopeptidase F (Peptidase_M3_N)

(115-184)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.34

98.507

0.663