Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4699_RS07490 Genome accession   NZ_CP137105
Coordinates   1489940..1490629 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2092     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1484940..1495629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS07465 - 1485534..1485923 (+) 390 WP_001865604.1 lanthionine synthetase LanC family protein -
  R4699_RS07470 - 1485823..1486410 (+) 588 WP_001822134.1 lanthionine synthetase LanC family protein -
  R4699_RS07475 - 1486453..1487685 (+) 1233 WP_050104856.1 MFS transporter -
  R4699_RS07480 cbpJ 1487803..1488801 (-) 999 WP_016399083.1 choline-binding protein CbpJ -
  R4699_RS07485 cbpC 1488820..1489842 (-) 1023 WP_050104855.1 choline-binding protein CbpC -
  R4699_RS07490 covR 1489940..1490629 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  R4699_RS07495 gndA 1490641..1492065 (-) 1425 WP_000158794.1 NADP-dependent phosphogluconate dehydrogenase -
  R4699_RS07500 mapZ 1492141..1493511 (-) 1371 WP_050104854.1 mid-cell-anchored protein MapZ -
  R4699_RS07505 - 1493524..1494681 (-) 1158 WP_050104853.1 class I SAM-dependent RNA methyltransferase -
  R4699_RS07515 gpsB 1495167..1495496 (-) 330 WP_000146520.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=895491 R4699_RS07490 WP_000518011.1 1489940..1490629(-) (covR) [Streptococcus pneumoniae strain 16H2092]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=895491 R4699_RS07490 WP_000518011.1 1489940..1490629(-) (covR) [Streptococcus pneumoniae strain 16H2092]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467