Detailed information NTG0895428

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: R4708_RS07640
• Genome accession: NZ_CP137104
• Coordinates: 1473500..1474567 (+)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae strain LM
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1468500..1479567

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4708_RS07625	amiA3	1469023..1471002 (+)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator
R4708_RS07630	amiC	1471069..1472565 (+)	1497	WP_000759905.1	ABC transporter permease	Regulator
R4708_RS07635	amiD	1472565..1473491 (+)	927	WP_000103702.1	oligopeptide ABC transporter permease OppC	Regulator
R4708_RS07640	amiE	1473500..1474567 (+)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
R4708_RS07645	amiF	1474578..1475504 (+)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
R4708_RS07650	-	1475579..1475764 (-)	186	Protein_1465	transposase	-
R4708_RS07655	-	1475957..1477303 (-)	1347	WP_001821303.1	IS1380-like element ISSpn5 family transposase	-
R4708_RS07660	-	1477470..1478613 (-)	1144	Protein_1467	transposase	-
R4708_RS07665	treR	1478770..1479480 (-)	711	WP_000760673.1	trehalose operon repressor	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=895428 R4708_RS07640 WP_000159553.1 1473500..1474567(+) (amiE) [Streptococcus pneumoniae strain LM]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=895428 R4708_RS07640 WP_000159553.1 1473500..1474567(+) (amiE) [Streptococcus pneumoniae strain LM]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541