Detailed information NTG0895417

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R4708_RS07010
• Genome accession: NZ_CP137104
• Coordinates: 1367690..1368727 (+)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain LM
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1362690..1373727

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4708_RS06975	yidC	1362725..1363651 (-)	927	WP_000835948.1	membrane protein insertase YidC	-
R4708_RS06980	-	1363729..1364007 (-)	279	WP_001174613.1	acylphosphatase	-
R4708_RS06985	-	1364041..1364781 (+)	741	WP_000152701.1	RNA methyltransferase	-
R4708_RS06990	-	1364837..1365520 (+)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
R4708_RS06995	asnA	1365632..1366624 (+)	993	WP_000747993.1	aspartate--ammonia ligase	-
R4708_RS07000	rsmD	1366689..1367228 (+)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R4708_RS07005	coaD	1367218..1367706 (+)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
R4708_RS07010	sepM	1367690..1368727 (+)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
R4708_RS07015	-	1368785..1369015 (+)	231	WP_000615437.1	DUF1146 family protein	-
R4708_RS07020	murA	1369039..1370322 (+)	1284	WP_317830009.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R4708_RS07025	-	1370315..1370503 (+)	189	WP_317830010.1	DNA-directed RNA polymerase subunit beta	-
R4708_RS07030	endA	1370542..1371366 (+)	825	WP_317830011.1	DNA/RNA non-specific endonuclease	Machinery gene
R4708_RS07035	-	1371519..1372850 (+)	1332	WP_317830012.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=895417 R4708_RS07010 WP_000727280.1 1367690..1368727(+) (sepM) [Streptococcus pneumoniae strain LM]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=895417 R4708_RS07010 WP_000727280.1 1367690..1368727(+) (sepM) [Streptococcus pneumoniae strain LM]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591