Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R4708_RS07030 Genome accession   NZ_CP137104
Coordinates   1370542..1371366 (+) Length   274 a.a.
NCBI ID   WP_317830011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LM     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1365542..1376366
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4708_RS06995 asnA 1365632..1366624 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  R4708_RS07000 rsmD 1366689..1367228 (+) 540 WP_000706960.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R4708_RS07005 coaD 1367218..1367706 (+) 489 WP_001280766.1 pantetheine-phosphate adenylyltransferase -
  R4708_RS07010 sepM 1367690..1368727 (+) 1038 WP_000727280.1 SepM family pheromone-processing serine protease Regulator
  R4708_RS07015 - 1368785..1369015 (+) 231 WP_000615437.1 DUF1146 family protein -
  R4708_RS07020 murA 1369039..1370322 (+) 1284 WP_317830009.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R4708_RS07025 - 1370315..1370503 (+) 189 WP_317830010.1 DNA-directed RNA polymerase subunit beta -
  R4708_RS07030 endA 1370542..1371366 (+) 825 WP_317830011.1 DNA/RNA non-specific endonuclease Machinery gene
  R4708_RS07035 - 1371519..1372850 (+) 1332 WP_317830012.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29772.35 Da        Isoelectric Point: 9.9527

>NTDB_id=895418 R4708_RS07030 WP_317830011.1 1370542..1371366(+) (endA) [Streptococcus pneumoniae strain LM]
MNKKTRQTLIGLLVLLLLSAGSYYIKQTELGNQAAKTKMSQKSQSPDAPGQALAESVLTDAVKSQIKGSLEWNGAGAFIV
NGNKTNLNAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=895418 R4708_RS07030 WP_317830011.1 1370542..1371366(+) (endA) [Streptococcus pneumoniae strain LM]
ATGAACAAAAAAACAAGACAGACACTGATTGGTTTGCTAGTGTTATTGCTCTTATCTGCGGGGAGCTATTATATTAAGCA
GACTGAACTAGGAAATCAGGCTGCTAAGACAAAAATGAGTCAGAAAAGTCAATCACCAGACGCGCCTGGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAAAGCCAAATAAAAGGGAGTCTGGAGTGGAACGGGGCTGGTGCTTTTATCGTC
AATGGTAATAAAACAAACCTAAATGCCAAGGTTTCAAGTAAGCCCTACGCTGATAATAAAACAAAGACAGTGGGCAAGGA
AACAGTGCCAACCGTGGCTAATGCCCTCTTGTCTAAGGCTACTCGCCAGTACAAGAATCGTGAAGAAACTGGGAATGGTT
CGACTTCATGGACTCCGCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAC
TTGTTAGGCTATGCCTTAATCGGTGGATTGGATGGTTTTGATGCCTCGACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCGCAAGCCGAGGATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGATC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTATGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCAGATGGAGAATTGGAATTTAATGTCCTAGTTCCCAATGTTCAAAAAGGGCTTCAACTGGATTACCGAAC
TGGAGAAGTCACTGTTACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

92.701

100

0.927
  endA Streptococcus pneumoniae D39

92.701

100

0.927
  endA Streptococcus pneumoniae R6

92.701

100

0.927
  endA Streptococcus pneumoniae TIGR4

92.701

100

0.927