Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4708_RS03375 Genome accession   NZ_CP137104
Coordinates   699408..700097 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LM     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 694408..705097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4708_RS03350 - 695094..695452 (+) 359 Protein_667 lantibiotic-modifying protein -
  R4708_RS03355 - 695352..695822 (+) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  R4708_RS03360 - 695981..697213 (+) 1233 WP_000765684.1 MFS transporter -
  R4708_RS03365 cbpJ 697331..698329 (-) 999 WP_000771129.1 choline-binding protein CbpJ -
  R4708_RS03370 cbpC 698348..699310 (-) 963 WP_000698035.1 choline-binding protein CbpC -
  R4708_RS03375 covR 699408..700097 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  R4708_RS03380 gndA 700109..701533 (-) 1425 WP_000158792.1 NADP-dependent phosphogluconate dehydrogenase -
  R4708_RS03385 mapZ 701609..703003 (-) 1395 WP_000039290.1 mid-cell-anchored protein MapZ -
  R4708_RS03390 - 703016..704173 (-) 1158 WP_000711398.1 class I SAM-dependent RNA methyltransferase -
  R4708_RS03400 gpsB 704659..705000 (-) 342 WP_000200644.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=895384 R4708_RS03375 WP_000518011.1 699408..700097(-) (covR) [Streptococcus pneumoniae strain LM]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=895384 R4708_RS03375 WP_000518011.1 699408..700097(-) (covR) [Streptococcus pneumoniae strain LM]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467