Detailed information    

insolico Bioinformatically predicted

Overview

Name   HI0659   Type   Machinery gene
Locus tag   R4709_RS02490 Genome accession   NZ_CP137102
Coordinates   499823..500089 (-) Length   88 a.a.
NCBI ID   WP_001820593.1    Uniprot ID   A0A6I3UU84
Organism   Streptococcus pneumoniae strain 16H3071-2     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 500774..510592 499823..500089 flank 685
IScluster/Tn 500167..500618 499823..500089 flank 78


Gene organization within MGE regions


Location: 499823..510592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4709_RS02490 HI0659 499823..500089 (-) 267 WP_001820593.1 helix-turn-helix domain-containing protein Machinery gene
  R4709_RS02495 - 500173..500618 (-) 446 Protein_496 helix-turn-helix domain-containing protein -
  R4709_RS02500 - 500774..501775 (+) 1002 WP_277779612.1 endonuclease/exonuclease/phosphatase family protein -
  R4709_RS02505 pheT 501843..504245 (-) 2403 WP_277779613.1 phenylalanine--tRNA ligase subunit beta -
  R4709_RS02510 - 504322..504831 (-) 510 WP_000619950.1 N-acetyltransferase -
  R4709_RS02515 pheS 504831..505877 (-) 1047 WP_001818763.1 phenylalanine--tRNA ligase subunit alpha -
  R4709_RS02520 - 506469..507884 (-) 1416 WP_000151832.1 glycoside hydrolase family 1 protein -
  R4709_RS02525 - 507897..509735 (-) 1839 WP_050119122.1 beta-glucoside-specific PTS transporter subunit IIABC -
  R4709_RS02530 licT 509753..510592 (-) 840 WP_050205510.1 BglG family transcription antiterminator LicT -

Sequence

Protein


Download         Length: 88 a.a.        Molecular weight: 9670.12 Da        Isoelectric Point: 4.3934

>NTDB_id=895231 R4709_RS02490 WP_001820593.1 499823..500089(-) (HI0659) [Streptococcus pneumoniae strain 16H3071-2]
MEGCPSELFSKEEILESDMRVAIMSELIEARHEQGINQRKLEELSGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAV
VPLEQGKS

Nucleotide


Download         Length: 267 bp        

>NTDB_id=895231 R4709_RS02490 WP_001820593.1 499823..500089(-) (HI0659) [Streptococcus pneumoniae strain 16H3071-2]
TTGGAAGGATGTCCATCTGAGCTCTTTAGCAAGGAGGAAATCCTTGAAAGTGATATGCGAGTGGCTATTATGAGCGAGTT
GATTGAAGCTAGACATGAACAAGGAATCAATCAGAGAAAGCTAGAAGAACTCAGTGGAGTGAGTCAACCTGTCATAGCTA
GGATGGAAACAGGAGAGAGCAGTCTTCAGTTGGATACGGTCTTAAAAGTTCTAACCAGTCTAGGAAAGACACTAGCAGTC
GTTCCACTTGAACAGGGGAAAAGTTGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(28-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I3UU84

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  HI0659 Haemophilus influenzae Rd KW20

55.844

87.5

0.489