Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4710_RS07745 Genome accession   NZ_CP137101
Coordinates   1462615..1463304 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1457615..1468304
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS07720 gpsB 1457724..1458053 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R4710_RS07730 - 1458539..1459696 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  R4710_RS07735 mapZ 1459709..1461103 (+) 1395 WP_061747125.1 mid-cell-anchored protein MapZ -
  R4710_RS07740 gndA 1461179..1462603 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  R4710_RS07745 covR 1462615..1463304 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  R4710_RS07750 cbpC 1463402..1464427 (+) 1026 WP_050076089.1 choline-binding protein CbpC -
  R4710_RS07755 cbpJ 1464446..1465444 (+) 999 WP_050245264.1 choline-binding protein CbpJ -
  R4710_RS07760 - 1465562..1466794 (-) 1233 WP_000765692.1 MFS transporter -
  R4710_RS07765 - 1466837..1467424 (-) 588 WP_016397727.1 lanthionine synthetase LanC family protein -
  R4710_RS07770 - 1467324..1467713 (-) 390 WP_016397728.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=895204 R4710_RS07745 WP_000518011.1 1462615..1463304(+) (covR) [Streptococcus pneumoniae strain 16P2012-2]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=895204 R4710_RS07745 WP_000518011.1 1462615..1463304(+) (covR) [Streptococcus pneumoniae strain 16P2012-2]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467