Detailed information NTG0895170

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R4710_RS04095
• Genome accession: NZ_CP137101
• Coordinates: 774806..775843 (-)
• Length: 345 a.a.
• NCBI ID: WP_050245294.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P2012-2
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 769806..780843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4710_RS04070	-	770545..771876 (-)	1332	WP_000390042.1	hemolysin family protein	-
R4710_RS04075	endA	772167..772991 (-)	825	WP_050245293.1	DNA-entry nuclease EndA	Machinery gene
R4710_RS04080	-	773030..773218 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
R4710_RS04085	murA	773211..774494 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R4710_RS04090	-	774518..774748 (-)	231	WP_078102751.1	DUF1146 family protein	-
R4710_RS04095	sepM	774806..775843 (-)	1038	WP_050245294.1	SepM family pheromone-processing serine protease	Regulator
R4710_RS04100	coaD	775827..776315 (-)	489	WP_044811672.1	pantetheine-phosphate adenylyltransferase	-
R4710_RS04105	rsmD	776305..776844 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R4710_RS04110	asnA	776909..777901 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
R4710_RS04115	-	778013..778696 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
R4710_RS04120	-	778752..779492 (-)	741	WP_000152674.1	RNA methyltransferase	-
R4710_RS04125	-	779526..779804 (+)	279	WP_001174613.1	acylphosphatase	-
R4710_RS04130	yidC	779882..780808 (+)	927	WP_000835944.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37479.54 Da
• Isoelectric Point: 5.2280

>NTDB_id=895170 R4710_RS04095 WP_050245294.1 774806..775843(-) (sepM) [Streptococcus pneumoniae strain 16P2012-2]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKGIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=895170 R4710_RS04095 WP_050245294.1 774806..775843(-) (sepM) [Streptococcus pneumoniae strain 16P2012-2]
ATGAAAAAAAAGATTAGATGGCCCTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGGTATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591