Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R4710_RS04075 Genome accession   NZ_CP137101
Coordinates   772167..772991 (-) Length   274 a.a.
NCBI ID   WP_050245293.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 767167..777991
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS04070 - 770545..771876 (-) 1332 WP_000390042.1 hemolysin family protein -
  R4710_RS04075 endA 772167..772991 (-) 825 WP_050245293.1 DNA-entry nuclease EndA Machinery gene
  R4710_RS04080 - 773030..773218 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  R4710_RS04085 murA 773211..774494 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R4710_RS04090 - 774518..774748 (-) 231 WP_078102751.1 DUF1146 family protein -
  R4710_RS04095 sepM 774806..775843 (-) 1038 WP_050245294.1 SepM family pheromone-processing serine protease Regulator
  R4710_RS04100 coaD 775827..776315 (-) 489 WP_044811672.1 pantetheine-phosphate adenylyltransferase -
  R4710_RS04105 rsmD 776305..776844 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R4710_RS04110 asnA 776909..777901 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29977.74 Da        Isoelectric Point: 10.1700

>NTDB_id=895169 R4710_RS04075 WP_050245293.1 772167..772991(-) (endA) [Streptococcus pneumoniae strain 16P2012-2]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQAPEVPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=895169 R4710_RS04075 WP_050245293.1 772167..772991(-) (endA) [Streptococcus pneumoniae strain 16P2012-2]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGCCTGAAGTTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

97.81

100

0.978
  endA Streptococcus pneumoniae D39

97.81

100

0.978
  endA Streptococcus pneumoniae R6

97.81

100

0.978
  endA Streptococcus pneumoniae TIGR4

97.81

100

0.978