Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R4710_RS04015 Genome accession   NZ_CP137101
Coordinates   755498..756118 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 750498..761118
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS03990 recA 750876..752042 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R4710_RS03995 cinA 752097..753353 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  R4710_RS04000 brpA 753437..754453 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  R4710_RS04005 - 754461..754979 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  R4710_RS04010 tsaE 754969..755412 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R4710_RS04015 comM 755498..756118 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R4710_RS04020 - 756501..757364 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  R4710_RS04025 - 757553..757723 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  R4710_RS04030 - 758038..758334 (+) 297 WP_000911560.1 lactococcin 972 family bacteriocin -
  R4710_RS04035 - 758437..760452 (+) 2016 WP_050245292.1 DUF1430 domain-containing protein -
  R4710_RS04040 - 760454..761086 (+) 633 WP_000571432.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=895168 R4710_RS04015 WP_000839908.1 755498..756118(-) (comM) [Streptococcus pneumoniae strain 16P2012-2]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=895168 R4710_RS04015 WP_000839908.1 755498..756118(-) (comM) [Streptococcus pneumoniae strain 16P2012-2]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTACTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369