Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   R4710_RS02225 Genome accession   NZ_CP137101
Coordinates   427730..428962 (-) Length   410 a.a.
NCBI ID   WP_000106350.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 422730..433962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS02195 - 422917..423885 (+) 969 WP_000080999.1 NAD(P)/FAD-dependent oxidoreductase -
  R4710_RS02200 whiA 423919..424830 (-) 912 WP_317805003.1 DNA-binding protein WhiA -
  R4710_RS02205 - 424827..425804 (-) 978 WP_001231069.1 YvcK family protein -
  R4710_RS02210 rapZ 425801..426691 (-) 891 WP_000163029.1 RNase adapter RapZ -
  R4710_RS02215 - 426743..427123 (-) 381 WP_001140412.1 RidA family protein -
  R4710_RS02220 yihA 427134..427721 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  R4710_RS02225 clpX 427730..428962 (-) 1233 WP_000106350.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  R4710_RS02230 - 428994..429164 (-) 171 WP_000442275.1 hypothetical protein -
  R4710_RS02235 - 429164..429670 (-) 507 WP_000162486.1 dihydrofolate reductase -
  R4710_RS02240 - 429800..430318 (-) 519 WP_000229874.1 DNA starvation/stationary phase protection protein -
  R4710_RS02245 lytC 430815..432319 (-) 1505 Protein_446 choline binding-anchored murein hydrolase LytC -
  R4710_RS02250 tpiA 432357..433115 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  R4710_RS02255 - 433213..433890 (-) 678 WP_000221604.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45812.38 Da        Isoelectric Point: 4.4578

>NTDB_id=895152 R4710_RS02225 WP_000106350.1 427730..428962(-) (clpX) [Streptococcus pneumoniae strain 16P2012-2]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=895152 R4710_RS02225 WP_000106350.1 427730..428962(-) (clpX) [Streptococcus pneumoniae strain 16P2012-2]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGAACGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATTGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.341

100

0.863
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.965

98.049

0.559